Results 71 to 80 of about 3,010,874 (320)

Identifying Mazama gouazoubira (Artiodactyla; Cervidae) chromosomes involved in rearrangements induced by doxorubicin

Genetics and Molecular Biology, 2017
The process of karyotype evolution in Cervidae from a common ancestor (2n = 70, FN = 70) has been marked by complex chromosomal rearrangements. This ancestral karyotype has been retained by the current species Mazama gouazoubira (Fischer 1814), for which
Iara Maluf Tomazella, Vanessa Veltrini Abril, José Maurício Barbanti Duarte   +2 more
doaj   +1 more source

Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype

Nature Genetics
Chromosomal instability is a major driver of intratumoral heterogeneity (ITH), promoting tumor progression. In the present study, we combined structural variant discovery and nucleosome occupancy profiling with transcriptomic and immunophenotypic changes
Aino-Maija Leppä, Karen Grimes, Hyobin Jeong, Frank Y. Huang, Álvaro Andrades, A. Waclawiczek, T. Boch, A. Jauch, S. Renders, Patrick Stelmach, C. Müller-Tidow, D. Karpova, Markus Sohn, F. Grünschläger, Patrick Hasenfeld, Eva Benito Garagorri, Vera Thiel, A. Dolnik, Bernardo Rodriguez-Martin, L. Bullinger, Krzysztof Mrózek, Ann-Kathrin Eisfeld, Alwin Krämer, A. Sanders, J. Korbel, A. Trumpp   +25 more
semanticscholar   +1 more source

A case of intersex occurrence in Steindachneridion parahybae (Steindachner, 1877) (Siluriformes: Pimelodidae) under captivity condition: A cytogenetic and morphological study [PDF]

, 2016
Poco se sabe sobre la biología reproductiva de Steindachneridion parahybae , una especie de teleósteo gonocorístico en peligro de extinción que habita la cuenca del río Paraíba do Sul y en éste trabajo se describe por primera vez la aparición de ...
Caneppele, Danilo, Honji, Renato Massaaki, Lo Nostro, Fabiana Laura, Moreira, Renata G., Pandolfi, Matias   +4 more
core   +2 more sources

Female Meiosis Drives Karyotypic Evolution in Mammals [PDF]

Genetics, 2001
Abstract Speciation is often accompanied by changes in chromosomal number or form even though such changes significantly reduce the fertility of hybrid intermediates. We have addressed this evolutionary paradox by expanding the principle that nonrandom segregation of chromosomes takes place whenever human or mouse females are ...
F, Pardo-Manuel de Villena, C, Sapienza
openaire   +2 more sources

Mammalian karyotype evolution [PDF]

, 2009
Kariotip neke jedinke se odnosi na broj, veličinu i izgled njezinih kromosoma. Kromosomi pojedinih vrsta predstavljaju širok spektar raznolikosti, od broja do njihove morfologije.
Jurković, Sven
core   +2 more sources

Homologies in human and Macasa fuscata chromosomes revealed by in situ suppression hybridization with human chromosome specific DNA libraries [PDF]

, 1992
We established chromosomal homologies between all chromosomes of the human karyotype and that of an old world monkey (Macaca fuscata) by chromosomal in situ suppression (CISS) hybridization with human chromosome specific DNA libraries.
Cremer, Thomas, Jauch, Anna, Stanyon, Roscoe, Wienberg, Johannes   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

23rd International Colloquium on Animal Cytogenetics and Genomics (23 ICACG) June 9–12, 2018, Saint-Petersburg, Russia

Comparative Cytogenetics, 2018
In memory of Ingemar Gustavsson 23rd International Colloquium on Animal Cytogenetics and Genomics (23 ICACG) took place in June 9–12, 2018 in Saint-Petersburg, Russia. Organized biennially, the Colloquium runs from 1970.
Svetlana Galkina, Maria Vishnevskaya
doaj   +3 more sources

Karyotypic evolution in a human mucoepidermoid carcinoma [PDF]

Hereditas, 2008
Chromosomes were studied in cultured material from two different areas of a human mucoepidermoid carcinoma. The detailed banding analyses showed no less than 41 different karyotypes. Comparisons between these revealed (1) that the tumour probably had originated with a normal, diploid stemline; (2) that the progression had mainly proceeded by steps in a
J, Mark, J, Sandros, B, Wedell, R, Dahlenfors, G, Stenman   +4 more
openaire   +2 more sources