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Cordocentesis for rapid karyotyping
American Journal of Obstetrics and Gynecology, 1990Pure fetal blood was obtained by cordocentesis in 101 fetuses of 96 patients at 15 to 38 weeks' gestation. Rapid karyotype was obtained within 2 to 4 days by fetal lymphocyte culture. Chromosomal abnormality was detected in 12 (11.9%) fetuses.
D M, Shah +4 more
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Heterochromatin, colchicine, and karyotype
Chromosoma, 1965Species of Chilocorus differ in chromosome number owing to centric fusion of metacentric chromosomes. The concomitant loss of arms is tolerated because in all unfused chromosomes one arm is completely heterochromatic, the other euchromatic. Under the influence of colchicine, the arms of unfused and fused chromosomes contract differentially.
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Dynamics of karyotype evolution
Chaos: An Interdisciplinary Journal of Nonlinear ScienceIn the evolution of species, the karyotype changes with a timescale of tens to hundreds of thousand years. In the development of cancer, the karyotype often is modified in cancerous cells over the lifetime of an individual. Characterizing these changes and understanding the mechanisms leading to them has been of interest in a broad range of disciplines
Elena Kuzmin +3 more
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