Results 41 to 50 of about 124,374 (336)

Karyotyping Mouse Cells [PDF]

open access: yesCold Spring Harbor Protocols, 2008
INTRODUCTIONThe majority of mouse chromosome preparations for banding are now made by air-drying and, in essence, require the production of a cell suspension as a starting point. Some samples such as blood cultures, ascitic fluids, or cells growing in suspension will already be in suspension; others, such as bone marrow, solid tumors, or cells growing ...
Andras, Nagy   +3 more
openaire   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

An Unusual Origin of Fetal Lymphangioma Filling Right Axilla [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Fetal lymphangioma is a hamartomatous congenital anomaly of the lymphatic system, which is embracing the fetal skin (sometimes mucous membranes) and the subcutaneous tissue.
Ali Ozgur Ersoy   +4 more
doaj   +1 more source

Acute non-lymphoblastic leukemia: characteristics of cytogenetic anomalies and their influence on clinical course of the disease

open access: yesОнкогематология, 2022
Cytogenetic changes in bone marrow cells and their influence on clinical course of the disease were analyzed in 106 patients with acute non-lymphoblastic leukemia (ANLL).
A. M. Vakulchuk   +4 more
doaj   +1 more source

Molecular Karyotyping in Children and Adolescents with Gender Dysphoria

open access: yesTransgender Health, 2018
Purpose: The presence of a disorder of sexual development (DSD) acts as a diagnostic specifier for gender dysphoria (GD) under DSM-5, while the International Classification of Diseases (ICD)-10 specifically states that its equivalent diagnosis, gender ...
Ken C. Pang   +3 more
semanticscholar   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

open access: yesAdvanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang   +8 more
wiley   +1 more source

Swyer Syndrome in Phenotypic Female with 46,XY Karyotype [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Individuals with Swyer syndrome have an XY karyotype and are phenotypically female. The prevalence of Swyer Syndrome is about 1 in 30,000 and it is an extremely rare condition.
D Prashanth Shetty   +3 more
doaj   +1 more source

Analyzing a clinical case of married couple with combined infertility

open access: yesАкушерство, гинекология и репродукция, 2022
Infertility is a disease of the reproductive system characterized by lacked clinical pregnancy after 12 or more months of regular unprotected sex. To diagnose the causes and choose the tactics of infertility treatment, a personalized approach to each ...
A. V. Ledina, G. G. Ketova
doaj   +1 more source

Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways

open access: yesAdvanced Science, EarlyView.
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang   +12 more
wiley   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

open access: yesAdvanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang   +13 more
wiley   +1 more source

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