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2019
An endemic osteochondral disease, Kashin-Beck disease (KBD), is widely found in the diagonal southern-west to northern-east zone in China and North Korea and in the Eastern Siberia of Russia. There is evidence that in China alone 1.3 million individuals have some level symptom of the syndrome, while the amount may even be underestimated.
Xiong Guo +10 more
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An endemic osteochondral disease, Kashin-Beck disease (KBD), is widely found in the diagonal southern-west to northern-east zone in China and North Korea and in the Eastern Siberia of Russia. There is evidence that in China alone 1.3 million individuals have some level symptom of the syndrome, while the amount may even be underestimated.
Xiong Guo +10 more
openaire +1 more source
Kashin-Beck Disease in Sichuan, China
JCR: Journal of Clinical Rheumatology, 2012The objective of the study was to identify adults with symptomatic Kashin-Beck disease (KBD) and observe the efficacy and safety of diclofenac sodium, naproxen, and glucosamine hydrochloride in these adult patients in Rang-tang (Sichuan Province), China.One hundred eighty-three adult patients with KBD were enrolled into this open study.
Wei, Liu +9 more
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[Kashin-Beck disease in Israel?].
Harefuah, 2002This is a case report of a 21 year old young man who suffers from severe early bilateral hip joint osteoarthrosis. Due to this surprising finding we discuss the differential diagnosis between Kashin-Beck disease, an endemic disease of the patients prior living area (east Siberia) and severe hip joint damage secondary to juvenile rheumatoid arthritis ...
Alexander, Rozin +3 more
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Iodine, Selenium Deficiency and Kashin–Beck Disease
2009This chapter deals with diseases where both iodine and selenium deficiency play a role in disease causation and particularly with Kashin-Beck Disease (KBD). KBD is an osteoarthropathy endemic in China and Tibet. The condition appears between the ages of 5 and 15 years, and leads to varying degrees of disability throughout adult life.
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Selenium and Kashin-Beck Disease
1996Kashin-Beck Disease (KBD) which hardly attracts attention in the west has been mainly found in remote and poor areas in China. The characteristics of the disease are short stature and deformed joints due to a focalised destruction of the chondrocytes of the articular cartilage and the growth zone (1). Although some factors have been found to be related
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CHAPTER 31. Selenium and Kashin–Beck Disease
2015Kashin–Beck disease (KBD) is an osteochondropathy endemic in China and other parts of Asia. A relationship between selenium (Se) deficiency and KBD was first noted in China in the 1970s; the disease was mainly found in low-Se areas. As Se content in water, soil, and grain were low in these areas, the nutritional status of local inhabitants was also Se ...
Xiong Guo, Yu-jie Ning, Xi Wang
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Association of oxidative stress and Kashin–Beck disease integrated Meta and Bioinformatics analysis
Osteoarthritis and Cartilage, 2022J Zuo
exaly
Correlation of matrix metalloproteinases and Kashin-Beck disease
2014Objective: To investigate the expressions of matrix metalloproteinases(MMPs) in Kashin-Beck disease(KBD) cartilage as well as in a KBD rat model of T-2 toxin poisoning under selenium deficient conditions, and to investigate the effect of T-2 toxin on MMP-13 expression in human chondrocytes in vitro in order to determine a possible mechanism underlying ...
Chen, Jinghong +7 more
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Defective autophagy in chondrocytes with Kashin-Beck disease but higher than osteoarthritis
Osteoarthritis and Cartilage, 2014Jun Zheng, H Shan, Xinyu Guo
exaly