Results 21 to 30 of about 1,107,275 (178)

Game mechanics and why they are employed: What we know about gamification so far

Issues and Trends in Educational Technology, 2018
This literature review addresses the research surrounding gamification in online learning, focusing on the game mechanics studied in conjunction with the pedagogical aspirations they were employed to support.
Craig Howard, Katherine Bevins
doaj   +2 more sources

Intimate partner violence perpetration and mental health service use in England: analysis of nationally representative survey data

BJPsych Open, 2023
Background Intimate partner violence perpetration (IPVP) is associated with psychiatric disorders, but an association with mental health service use has not been fully established and is relevant for policy.
Vishal Bhavsar, Sally McManus, Katherine Saunders, Louise M. Howard   +3 more
doaj   +1 more source

Mobile consumers influence the shoreward edge of intertidal seagrass ecosystems

Journal of Animal Ecology, EarlyView.
Ecological paradigms suggest that the environmentally stressful edge of a habitat is determined by physical factors. The work finds that, counter to these paradigms, an environmentally stressful edge can also be impacted by biotic interactions and are more complex than suggested.
Stephanie R. Valdez, Carter S. Smith, Catherine L. Brenner, Avery B. Paxton, Brian R. Silliman   +4 more
wiley   +1 more source

Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions

Particle and Fibre Toxicology, 2017
Background As nanoparticles (NPs) become more prevalent in the pharmaceutical industry, questions have arisen from both industry and regulatory stakeholders about the long term effects of these materials. This study was designed to evaluate whether gold (
James L. Weaver, Grainne A. Tobin, Taylor Ingle, Simona Bancos, David Stevens, Rodney Rouse, Kristina E. Howard, David Goodwin, Alan Knapton, Xiaohong Li, Katherine Shea, Sharron Stewart, Lin Xu, Peter L. Goering, Qin Zhang, Paul C. Howard, Jessie Collins, Saeed Khan, Kidon Sung, Katherine M. Tyner   +19 more
doaj   +1 more source

A History of ‘Religious History’

Journal of Religious History, EarlyView.
As a category denoting the analysis of religious actors across history disinterestedly and on their own terms, “religious history” is a relatively recent coinage. This article offers a brief contextualisation of the emergence of the field in the twentieth century. It distinguishes “religious history” from an older, “confessional” mode of ecclesiastical
Joshua Bennett
wiley   +1 more source

Delivery and adherence of biomarker‐guided antibiotic treatment protocols in the ADAPT‐Sepsis clinical trial: an in‐trial descriptive process evaluation of daily procalcitonin‐ and C‐reactive protein‐guided protocols

Anaesthesia, EarlyView.
Summary Introduction Biomarker‐guided antibiotic protocols using daily procalcitonin or C‐reactive protein have been proposed to optimise antibiotic duration in sepsis. This pre‐planned process evaluation of the ADAPT‐Sepsis trial examined delivery and clinician adherence to procalcitonin‐ and C‐reactive protein‐guided protocols.
Ranjit Lall, Anower Hossain, Ruth Poole, Christina Lloydwin, Harley Anderson, Judith White, Paul Dark, on behalf of the ADAPT‐Sepsis collaborators, Julian Bion, Alasdair MacGowan, Paul McCrone, Maurice O'Kane, Ben Attwood, Gordon Sturmey, Janet Prentice, Ly‐mee Yu, Tom Clutton‐Brock, Duncan Young, John Simpson, Kay Marshall, Simon Gates, Judith White, Dipesh Mistry, Scott Regan, Nicola McGowan, Dalbir Kaur, Chen Ji, Nessa Nevels, Ingeborg D Welters, Karen Williams, David Shaw, Victoria Waugh, Julie Patrick‐Heselton, Carol Paisley, Suzannah Phillips, Emily Johnson, Jaime Fernandez Roman, Maria Lopez Martinez, Arra Mahiya, Daniel Watkin, Zachary Thomas, Andrew Davison, Sofia Farina, Maria Norris, Silvia Manes, Jin‐Xi Yuan, Josh Colfar, Caitlin Lythgoe, Ibrahim Almafreji, Lisa Bailey, Robert Parker, Ian Turner‐Bone, Laura Wilding, Michaela Lloyd, Harriet Murrant, Leanne Smith, Ben Morton, Dylan Middleton, William McCaig, Amie Hughes, Lucy Fuller, Dominic Kay, Sharon Barber, Jane Parez, Stephanie Lee, Reece Doonan, Lisa Swindells, Jessica Pendlebury, Jessica Holden, Jacob Hadfeild, Jay Naisbitt, Andrew Caxton, Emma Parkin, Daniel Horner, Anila Sukumaran, Benedict Gyamerah, Alice Dunombe, DR Chris Taylor, DR Wadhi Habeichi, Joanna Borzomato, Paul Ferris, Justin Roberts, James Nesbitt, Jonathan Clayton, John Macdonald, Alistair Roy, Anthony Rostron, Lindsey Woods, Sarah Cornell, Kimberley Rogerson, Jo Boxall, Trina Burns, Susan Cooper, Kirstie Knight, Sarah Constable, Laura Kenny, Jonathan Vernazza, Maxwell Richardson, Matthew Bickerton, Andrew Camplejohn, Roseanne Cope, Julie Sheriff, Helena Baker, Jessica Watson, Jodie Sedgwick, Simon Whiteley, Max Ridley, Richard Gould, Sarah Perrin, Elizabeth Wilby, Susan Trott, Sheila Salada, Sarah Watts, Zoe Friar, Bethan Ogg, Clare Howcroft, Kate Long, Alistair Morris, Julia Sampson, Alexandra Gibbins, Celia Peters, Megan Meredith, Alice Baddeley, Anthony Baidoo, Dan Harvey, Alexandra McCoy, Sophie Lubbock, David Ford, Amy Clark, Laura Lloyd, Mohammed Habib, Gemma Clark, Ian King, Carla Goode, Angela Sellick, Shova Sharma, Anita Assi, Jennifer Dengate, Matthew Grice, Laura Brammer, Chinyere Ajonu, Samuel Redgate, Wendy Smith, Manjinder Khakh, Hannah Howson‐Wells, Simon Atkin, Max Casbon, Frances Olsen, Bhavin Mistry, Victoria Mitchinson, Aysha Talbot, Iain McCullagh, Arti Gulati, Benjamin Brown, Stephanie Grieveson, Tara Shrestha, Ian Storey, Fatima Simoes, Verity Calder, Carole Hays, Maite Babio‐Galan, Deborah White, Jennifer Collins, Leigh Dunn, Susan Taylor, Luzgie Gavina, Tessa Wilkinson, Pamela Garcia, Lauren Butler, James Savage, Jayne Harwood, Sarah Cook, Stephen Hamilton, Jonathan Shelton, Ian Clement, Samantha Burn, Nathan Carroll, Lauren Clark, Lauren Ferguson, Sam Foggett, Alison Hague, Tracy Handley, Chelsea Hewison, Samantha Kitchener, Laura McEachan, Nicole McEwen, Ryan Perry, Olivia Purdy, Amie Thomson, Stephanie Williams, Glykeria Pakou, Helder Filipe, Margaret McNeil, Sara Mingo, Catarina Veiga, Poh Choo Teoh, Amitaa Maharajh, Mark De Neef, Coral Cole, Alex Ross, Mark Belsham, Shatha Abu‐Hijleh, Saida Solkar, Oghenemega Okotete, Peter D G Alexander, Luke Ward, Joanne Rothwell, Sherly George, Hannah Currie, Katharine Sellers, Karen Morris, Jan Hansel, Gavin Perkins, Jo Gresty, Ellie Reeves, Teresa Melody, Helen Taylor, Sara Bawa, Celinamma Maliaykal, William McIver, Mohamed Mooradun, Tay‐yibah Mohamed, Heather Willis, Aidan Butler, Amy Hooper, Adam Boulton, Lucie Linhartova, Rachel Smith, Daniel Park, Anna Dennis, Joyce Yeung, Hozefa Ebrahim, Neil Crooks, Sarah Milton‐White, Sarah Ballinger, Natalie Carling, Julia Sampson, Chloe Norman, Marie Thomas, Alexandra Nance, Emma Evans, Lesley Horton, Madhu Balasubramaniam, Rebecca Flanagan, Emma McKenna, Scott Latham, Danielle Hollick, Chinari P K Subudhi, Celia Chu, Katy Edwards, Rashmi Gupta, Carolyn Williams, Lindwe Mashangombe, Misbah Javed, Timothy Walsh, Maria Amamio, Gillian Andrew, Lucy Barclay, Sophie Birch, Kate Briton, Lisa‐Marie Butt, Sarah Clark, Jessica Crossan, Katherine Doverman, Michael Gillies, David Griffith, David Hope, Kallirroi Kefala, Ian Laurenson, Nazir Lone, Lucy Macdonald, Craig Marshall, Corrienne McCulloch, Gregor McNeill, Nicola Rea, Scott Simpson, Jo Singleton, Elzbieta Czarniak, Olga Lucia Moncayo Nieto, Joanne Thompson, Ceri Lynch, Bethan Gibson, Piroska Toth‐tarsoly, Zolton Auer, Daniel Law, Jayparaska Singh, Shaun Oram, Arsalan Zaki, Alan Dodd, Bethan Deacon, Lisa Roche, Leanne Jones, Justyna Smeaton, Kevin Agravante, Oladele Akinyoola, Keri Turner, Joanne Pugh, Sam Evans, Lisa Mellish, Angharad Rees, Geraint Lewis, John Burke, Nia Bromage, Nicola Llewellyn, Justine Evans, Marlo Constantino, Redmond P Tully, Andrew Drummond, Joy Dearden, Michelle Mulcahy, Carrole Blessen, Angiy Vian‐Michael, Grainne O'Connor, Jonathan Scargill, Sarah Winnard, James McNamee, Danny McAuley, Peter McGuigan, Kathyrn Ward, Justine Ward, Aisling O'Neill, Stephanie Finn, Erin Collins, Jackie Green, Christine Turley, Gerard Quinn, Matthew Adams, Chris Wright, Gareth McKeeman, Rory Loughlin, Lynsey Reilly, Heather Gallagher, Steve Coward, Rachel Morrison, Shondipon Laha, Sushruth Madanapalli Raghunath, Alex Jude Fonseca, Alexandra Williams, Sacha Connor, Rebecca Allock, Lisa Halsall, Sean McMullen, Jayanthi Rajasekar, Sarah Purvis, Isha Garg, Vijay Jagannathan, Hillie Corr, Magda Stefaniak, Simon Sinclair, Chris Wilson, David Brealey, Niall MacCallum, Ingrid Hass, Georgia Bercades, Deborah Smyth, Gladys Martir, Anna Reyes, Maria Alexandra Zapata Martinez, Laura Gallagher, Hodan Omer, Jonathan Bannard‐Smith, Deborah Paripoorani, Charlotte Taylor, Gregory Yates, Katharine Wylie, Sadiya Salah, Fionn Quilty, Stephen Bonner, Jeremy Henning, Amy Thompson, Jessica Jones, Steven Liggett, Craig Mower, Sarah Bircham, Bobette Kamangu, Abiola Shoremekun, Anitha Ratnakumar, Keith Hugill, Tom Lawton, Amy Robinson, Rafaq Azad, Megan Kitching, Chris Cockcroft, Louise Akeroyd, Jackie Todd, Susan Kimachia, Lisa Burgess, Shereen Bano, Fiona Jutsum, Laura Price, Susie Pajak, Hannah Gibson, Mark Bates, Karen Reid, Alison Bland, Alison Stephens, Denise Donaldson, Mandy Beekes, Jo Stickley, Colene Adams, Amy Bowes, Sanal Jose, Rebecca Wilcox, Rachel Rikunenko, Maria Houghton, Andrew Donnelly, Julie Summers, Christopher Mowatt, Katherine Richmond, Rebecca Jones, Tammy Davie, Michael Barnsley, Mick Pursglove, James Pearce, Philippa Lane, Natasha Cole, Megan Phillips, Joanna Jasiewicz, Sarah Hamad, Jyoti Sharma, Muhammad Adeeb, Mohammad Qasim, Lisa Barnsley, Louise Walton, Claire Wright, Helen Kaura, Cathy McCormack, Dave Latham, Emily Wynne, Catherine McCormack, Kathy Richmond, Christopher Thompson, Minnie Gellamucho, Jane Delaney, Michelle Davies, Elisa Sernicola, Lucy Bailey, Angelene Cope, Claire Hudson, Umar Mohyddin, Jack Lee, Ben Storey‐Waters, Faye Halliday, George Mathew, Sarah Birch, Dumindu Karangoda, Estefania Treus, Leanne Howard, Georgina Luck, Claire Gabriel, Richard Lowsby, Elijah Matovu, Katherine Pagett, Deborah Maren, Tenifayo Adeyemo, Hannah David, Mark Quiambao, Joanne Harold, Sheron Clarke, Valery Gurov, Anthony Mkandhla, Chris Duff, Helen Duce, Tony Whitehouse, Amy Clark, Liz Ratcliffe, Anna Casey, Natalie Dooley, Karen Ellis, Christopher Sheridan, Lisa Moody, Puja Mulholland, Rachel Webster, Samantha Harkett, Sophia Beddows, Caroline Dooley, Eamonn Reda, Stephanie Goundry, Elaine Spruce, Tonny Veenith, Dhruv Parekh, Natalie Walmsley, Malikah Saba, Rebecca Gill, Esther Thomas, Jaimin Patel, Mansoor Bangash, Craig Denmade, Sarah White, Rosie Clare, Ya‐Wen J Huang, Dawn Herbert, Lynn Rowbottom, Madeleine McGrady, Matt Thomas, Paul Thomas, Ruth Worner, Borislava Borislavova, Kati Hayes, Beverley Faulkner, Emma Gendall, Elizabeth Goff, Hayley Blackmore, Mike Spivey, Sarah Bean, Karen Burt, Anthea Pattterson, Lisa Vipond, Matthew Martin, Nick Vallotton, Samuel Waterman, Michael Kelsey, Ana Zuriaga‐Alvaro, Loreta Mostoles, Anezka Pratley, Nabeel Amiruddin, Helen Ashby, Gemma Wood, George Priestley, Phil Antil, Joseph Carter, David Yates, Rob Ferguson, Harriet Carter, Zoe Cinquina, Dewi Williams, Catherine Jardine, Karen Craik, Julia Anderson, Aditya Adhikarla, Christopher Bassford, Laura Wild, Jayachandran Radhakrishnan, Stacey Cotterall, Mandy Austin, Mark Wilkinson, Niall Harbison   +536 more
wiley   +1 more source

Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders

Molecular Neurodegeneration, 2020
Emerging evidence demonstrates that adaptive immunity influences the pathobiology of neurodegenerative disorders. Misfolded aggregated self-proteins can break immune tolerance leading to the induction of autoreactive effector T cells (Teffs) with ...
Jatin Machhi, Bhavesh D. Kevadiya, Ijaz Khan Muhammad, Jonathan Herskovitz, Katherine E. Olson, R. Lee Mosley, Howard E. Gendelman   +6 more
doaj   +1 more source

Adolescents' self‐diagnosis of mental disorders: a qualitative study of mental health clinicians' perspectives

Child and Adolescent Mental Health, EarlyView.
Background Concerns over self‐diagnosis of mental disorders among adolescents have been increasing, but very little empirical research exists to understand what clinicians think about this phenomenon or how it might impact psychological therapy. Methods Semi‐structured one‐to‐one interviews were conducted with 16 mental health professionals, exploring ...
Katie Cunningham‐Rowe, Lucy Foulkes
wiley   +1 more source

Evaluation of the safety and immunomodulatory effects of sargramostim in a randomized, double-blind phase 1 clinical Parkinson’s disease trial

npj Parkinson's Disease, 2017
Immune modulation: translating the benefits The immune system modulating drug sargramostim shows promising results in a small clinical trial with Parkinson’s disease (PD) patients.
Howard E. Gendelman, Yuning Zhang, Pamela Santamaria, Katherine E. Olson, Charles R. Schutt, Danish Bhatti, Bhagya Laxmi Dyavar Shetty, Yaman Lu, Katherine A. Estes, David G. Standaert, Elizabeth Heinrichs-Graham, LuAnn Larson, Jane L. Meza, Matthew Follett, Erica Forsberg, Gary Siuzdak, Tony W. Wilson, Carolyn Peterson, R. Lee Mosley   +18 more
doaj   +1 more source

Metformin and Severe Post‐COVID‐19 Outcomes Among Individuals With Diabetes Mellitus

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims We evaluated the relationship between metformin, one of the most commonly prescribed medications for individuals with diabetes, and COVID‐19 sequelae. Materials and Methods We evaluated a retrospective cohort of individuals in the National Clinical Cohort Collaborative with Type 2 diabetes mellitus and COVID‐19 who were prescribed ...
Zachary B. Dozier, Lin‐Chiun Wang, Yunwen Ji, A. Jerrod Anzalone, Oluwasolape Olawore, Ryan Hafen, Eric Hurwitz, Manav Kumar, Rena C. Patel, Ariana Budhihartanto, Mark van der Laan, John M. Colford Jr., Alan E. Hubbard, John B. Buse, Steven G. Johnson, Jane Reusch, Lauren E. Chan, Richard Moffitt, Rachel Wong, Carolyn Bramante, on behalf of the National Clinical Cohort Collaborative (N3C) Consortium, Adam B. Wilcox, Adam M. Lee, Alexis Graves, Jerrod) Anzalone, Amin Manna, Amit Saha, Amy Olex, Andrea Zhou, Andrew E. Williams, Andrew Southerland, Andrew T. Girvin, Anita Walden, Anjali A. Sharathkumar, Benjamin Amor, Benjamin Bates, Brian Hendricks, Brijesh Patel, Caleb Alexander, Carolyn Bramante, Cavin Ward‐Caviness, Charisse Madlock‐Brown, Christine Suver, Christopher Chute, Christopher Dillon, Chunlei Wu, Clare Schmitt, Cliff Takemoto, Dan Housman, Davera Gabriel, David A. Eichmann, Diego Mazzotti, Don Brown, Eilis Boudreau, Elaine Hill, Elizabeth Zampino, Emily Carlson Marti, Emily R. Pfaff, Evan French, Farrukh M. Koraishy, Federico Mariona, Fred Prior, George Sokos, Greg Martin, Harold Lehmann, Heidi Spratt, Hemalkumar Mehta, Hongfang Liu, Hythem Sidky, J. W. Awori Hayanga, Jami Pincavitch, Jaylyn Clark, Jeremy Richard Harper, Jessica Islam, Jin Ge, Joel Gagnier, Joel H. Saltz, Joel Saltz, Johanna Loomba, John Buse, Jomol Mathew, Joni L. Rutter, Julie A. McMurry, Justin Guinney, Justin Starren, Karen Crowley, Katie Rebecca Bradwell, Kellie M. Walters, Ken Wilkins, Kenneth R. Gersing, Kenrick Dwain Cato, Kimberly Murray, Kristin Kostka, Lavance Northington, Lee Allan Pyles, Leonie Misquitta, Lesley Cottrell, Lili Portilla, Mariam Deacy, Mark M. Bissell, Marshall Clark, Mary Emmett, Mary Morrison Saltz, Matvey B. Palchuk, Melissa A. Haendel, Meredith Adams, Meredith Temple‐O'Connor, Michael G. Kurilla, Michele Morris, Nabeel Qureshi, Nasia Safdar, Nicole Garbarini, Noha Sharafeldin, Ofer Sadan, Patricia A. Francis, Penny Wung Burgoon, Peter Robinson, Philip R. O. Payne, Rafael Fuentes, Randeep Jawa, Rebecca Erwin‐Cohen, Rena Patel, Richard A. Moffitt, Richard L. Zhu, Rishi Kamaleswaran, Robert Hurley, Robert T. Miller, Saiju Pyarajan, Sam G. Michael, Samuel Bozzette, Sandeep Mallipattu, Satyanarayana Vedula, Scott Chapman, Shawn T. O'Neil, Soko Setoguchi, Stephanie S. Hong, Steve Johnson, Tellen D. Bennett, Tiffany Callahan, Umit Topaloglu, Usman Sheikh, Valery Gordon, Vignesh Subbian, Warren A. Kibbe, Wenndy Hernandez, Will Beasley, Will Cooper, William Hillegass, Xiaohan Tanner Zhang   +148 more
wiley   +1 more source