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Temporal changes of hepatic drug-metabolizing enzymes mediated by hepatic ischemia-reperfusion injury and the protective effect of Oridonin. [PDF]

Sci Rep
Gu T, Dai F, Cai M, Zhang X, Xie D, Jiang H, Tian L, Yan L, Lan W, Lv H, Tang L, Li H, Liu Z.   +12 more
europepmc   +1 more source

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New ent-kaurane diterpenes with chiral epoxyangelate moieties from Wedelia prostrata

Chinese Chemical Letters, 2019
Four new ent-kaurane diterpenes with chiral epoxyangelate moieties, (2′R,3′R)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (1), (2′S,3′S)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (2), (2′S,3′R)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19 ...
Zhongnan Wu, Yu-bo Zhang, Wen Li, Neng-hua Chen, Qian-Wen Niu, Yingying Li, Qing-Guo Li, Danqing Yang, Yao-lan Li, Guocai Wang   +9 more
semanticscholar   +2 more sources

Cytotoxic Trachylobane and Kaurane Diterpenes from Psiadia punctulata

, 2020
Original NMR data (FIDs).
Souaibou Yaouba, A. Valkonen, Daniel von der Heiden, S. Lindblad, P. Coghi, B. Irungu, J. Midiwo, V. Wong, A. Yenesew, M. Erdélyi   +9 more
semanticscholar   +2 more sources

Unusual ent-Kaurane Diterpenes from the Coffea Cultivar S288 Coffee Beans and Molecular Docking to α-Glucosidase.

Journal of Agricultural and Food Chemistry, 2022
A total of 11 new (1-11) and 2 known (12 and 13) ent-kaurane diterpene derivatives were identified from the roasted beans of Coffea cultivar S288. Their structures were established by extensive spectroscopic analysis, including one- and two-dimensional ...
Defu Hong, G. Hu, Xingrong Peng, Xiaoyuan Wang, Yanbing Wang, Abdulbaset Al-Romaima, Zhongrong Li, M. Qiu   +7 more
semanticscholar   +1 more source

Ent-kaurane diterpenes isolated from n-hexane extract of Baccharis sphenophylla by bioactivity-guided fractionation target the acidocalcisomes in Trypanosoma cruzi.

Phytomedicine, 2021
BACKGROUND In the present work the bioactivity-guided fractionation of n-hexane extract from aerial parts of Baccharis sphenophylla (Asteraceae) against trypomastigote forms of Trypanosoma cruzi was performed.
T. A. da Costa-Silva, Matheus L. Silva, G. Antar, A. Tempone, J. Lago   +4 more
semanticscholar   +1 more source

The anti-inflammatory effects of two ent-kaurane diterpenes from the stems and leaves of Gochnatia decora.

Combinatorial chemistry & high throughput screening, 2021
AIM AND OBJECTIVES The Gochnatia decora (Kurz) A. L. Cabrera is a rare woody plant belonging to the family of Asteraceae. The bark of this plant is used in Chinese folk medicine to treat cough and pneumonia.
Yanfang Liu, Weifeng Dai, Qihui Cao, Mi Zhang   +3 more
semanticscholar   +1 more source

Three new ent-kaurane diterpenes from the herbs of Wedelia prostrata

Journal of Natural Medicines, 2016
Three new ent-kaurane diterpenes, 3α-angeloyloxy-17-hydroxy-ent-kaur-15-en-19-oic acid (1), 3α-tigloyloxy-17-hydroxy-ent-kaur-15-en-19-oic acid (2) and 3α-cinnamoyloxykaur-9(11),16-dien-19-oic acid (3), along with five known compounds (4-8), were isolated from the herbs of Wedelia prostrata (Asteraceae).
Zhongnan Wu, Yu-bo Zhang, Li Yang, Neng-hua Chen, Lin Jiang, Siqi Jiang, Guoqiang Li, Yao-lan Li, Guocai Wang   +8 more
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ent‐Kaurane‐Type Diterpenes Induce ROS‐Mediated Mitochondrial Dysfunction and Apoptosis by Suppress the Homologous Recombination DNA Repair in Triple‐Negative Breast Cancer Cells

Chemistry and Biodiversity, 2023
Six ent‐kaurane‐type diterpenes were isolated from the roots of Isodon ternifolia. Previous studies have shown that compounds 1 and 2 exhibited cytotoxicity against three human cancer cell lines (MCF‐7, A549, and HCT116), but its molecular mechanism has ...
Yikun Xie, Yifan Su, Zirou Liao, Xinran Liang, Jing Hua, Dawei Zhang, De-xuan Hu, Qian Yu   +7 more
semanticscholar   +1 more source