Results 41 to 50 of about 942 (144)
Anti-Neuroinflammatory ent-Kaurane Diterpenoids from Pteris multifida Roots
Molecules, 2016 Activated microglia are known to be a major source of cellular neuroinflammation which causes various neurodegenerative diseases, including Alzheimer’s disease.
Jung Wha Kim +3 more
doaj +1 more source
Theoretical Research into Anticancer Activity of Diterpenes Isolated from the Paraiban Flora
Natural Product Communications, 2014 Many studies of the scientific literature discuss the anticancer activity of diterpenes inhibiting the Akt/IKK/NF-κB pro-survival signaling cascade, mainly by the activation of serine/threonine phosphatase PP2A.
Luciana Scotti +6 more
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Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins
Molecules, 2012 Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species (Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially, mono- and di-acids, solubilized by sesquiterpene hydrocarbons. The sesquiterpenes and
Jamilly Kelly Oliveira Neves +5 more
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Diversity of the diterpenes in the leaves of Xylopia laevigata (Annonaceae) and their cytotoxicities
Química NovaThe phytochemical investigation of the hexane extract which was obtained from the leaves of Xylopia laevigata (Annonaceae) produced six terpenes. Among these, five diterpenes named abieta-7,13-dien-3-one, ent-7β-acetoxy-16β-hydroxy-kaurane, 4-epi ...
Emmanoel V. Costa +10 more
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STRUCTURE-ACTIVITY RELATIONSHIP STUDY OF DITERPENES FOR TREATMENT OF ALZHEIMER'S DISEASE
Química NovaAlzheimer's disease is an irreversible, degenerative and age-related disease which is growing more and more with the increase in life expectancy. Kaurane diterpenes are a class of natural products available in large amounts in nature and isolated from ...
Gabriel F. dos Santos +8 more
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COX-2 Inhibitory Activity of Cafestol and Analogs from Coffee Beans
Natural Product Communications, 2008 Two kaurane diterpenes, namely cafestol ( 1 ) and kahweol ( 2 ), were isolated from hydrolyzed fraction of the fixed oil of Ethiopian Coffea arabica unroasted beans, using AgNO 3 -impregnated silica gel chromatography. In addition, cafestol palmitate ( 3
Ilias Muhammad +8 more
doaj +1 more source
Kaurane-Type Diterpenes from Fern Frond Exudates
Zeitschrift für Naturforschung C, 1989 Abstract The viscid exudate found on fronds of the fern, Cheilanthes kaulfussii, consists of terpenoids in which flavonoid aglycones are dissolved. One of the terpenes is shown to be em-kaur-16-en-19-oic acid. The farinose frond exudate of Notholaena pallens contains this acid as the major constituent and its 3 R-hydroxy derivative ...
Peter Rüedi +3 more
openaire +1 more source
Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.The orthoquinone metabolites from plants have antimicrobial, antioxidant, antiviral, cytotoxic, and anti‐inflammatory effects. ABSTRACT The structural diversity of natural products is vast and fascinating, and they have been recognized as an enormously diverse source of new lead compounds.
Hidayat Hussain +5 more
wiley +1 more source
SYNTHETIC TRANSFORMATIONS OF ENT-KAURENOIC ACID [PDF]
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2015 This paper presents a review on kaurane diterpenes, covering various aspects of chemical and microbiological transformations of native ent-kaurenoic acid, namely, its reactions via COOH groups, double bonds and rearrangements of the carbon skeleton that ...
Olga Morarescu
doaj
Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.Oral squamous cell carcinoma (OSCC) is one of the leading causes of cancer‐related mortality in Taiwan. Natural products have long served as a valuable source of chemotherapeutic agents. In the present study, we investigated the antitumor effects of DOK, a diterpene derived from Adenostemma lavenia, a plant traditionally used an herbal tea, in OSCC ...
Kun-Chang Wu +5 more
wiley +1 more source