Results 71 to 80 of about 20,581 (189)

Pharmacological Activities of Alisma orientale against Nonalcoholic Fatty Liver Disease and Metabolic Syndrome: Literature Review

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Nonalcoholic fatty liver disease (NAFLD) is a rapidly emerging hepatic manifestation of metabolic syndrome. However, its unrevealed mechanism and complicated comorbidities have led to no specific medication, except for weight loss and lifestyle modification. Alisma orientale (Sam.) Juzep (A.
Eunsol Choi   +3 more
wiley   +1 more source

Schistosomicidal activity of kaurane, labdane and clerodane-type diterpenes obtained by fungal transformation

open access: yes, 2020
Schistosomiasis continues to be a huge challenge for researchers, pharmaceutical companies, and governments in developing countries. Diterpene compounds are good source for the development of novel potential leading compounds to treat schistosomiasis. We
L. Oliveira   +12 more
semanticscholar   +1 more source

Consequences of interspecific plant hybridization on metabolic diversity in naturally occurring hybrid swarms

open access: yesThe Plant Journal, Volume 123, Issue 4, August 2025.
Significance Statement Studies on the effect of hybridization on plant chemistry have mainly been conducted with crop plants and artificially created hybrids, and the few studies that have analyzed naturally occurring hybrids have either examined only a small number of plants and/or only a small number of metabolites.
Olga Zafra‐Delgado   +6 more
wiley   +1 more source

Phytochemical Benefits of Agroresidues as Alternative Nutritive Dietary Resource for Pig and Poultry Farming

open access: yesJournal of Chemistry, Volume 2018, Issue 1, 2018., 2018
The growing world population is challenging the animal products supply system, particularly in developing countries, where demand for meat and milk in 2050 is estimated to increase to 109% and 116%, respectively, amidst deteriorating livestock feed sources.
Matthew Achilonu   +5 more
wiley   +1 more source

Harnessing the Biocatalytic Potential of PtmO6, an α-Ketoglutarate-Dependent Dioxygenase from Platensimycin Biosynthesis, for the Chemoenzymatic Synthesis of Highly Oxidized ent-Kaurane Diterpenes

open access: yes, 2019
We demonstrate the utility of biocatalytic hydroxylation with PtmO6 in the chemoenzymatic total synthesis of three oxidized kaurane natural products.
Xiao Zhang   +5 more
semanticscholar   +1 more source

Brazilian Amazon Traditional Medicine and the Treatment of Difficult to Heal Leishmaniasis Wounds with Copaifera

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2017, Issue 1, 2017., 2017
The present study describes the use of the traditional species Copaifera for treating wounds, such as ulcers scarring and antileishmanial wounds. It also relates phytochemical studies, evaluation of the leishmanicidal activity, and toxicity. The species of Copaifera with a higher incidence in the Amazon region are Copaifera officinalis, Copaifera ...
Kelly Cristina Oliveira de Albuquerque   +9 more
wiley   +1 more source

Chemistry of South African Lamiaceae: Structures and Biological Activity of Terpenoids [PDF]

open access: yes, 2018
South Africa flora is one of the most important mega floras with high endemic species percentage. Lamiaceae is an important family in South Africa with ±308 species in 41 genera and contains many important plants (~23%) traditionally used for treatment ...
Hussein, Ahmed A.
core   +2 more sources

Antiangiogenic Effect of Ethanol Extract of Vigna angularis via Inhibition of Phosphorylation of VEGFR2, Erk, and Akt

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2015, Issue 1, 2015., 2015
Though dietary azuki bean (Vigna angularis) seed containing antioxidant proanthocyanidins was known to have multibiological activities including antioxidant, hypotensive, anti‐inflammatory, and immunomodulatory activities, the antiangiogenic activity of ethanol extract of Vigna angularis (EVA) was never reported so far.
Oh Sung Kwon   +4 more
wiley   +1 more source

The microbiological transformation of two 15B-hydroxy-ent-kaurene diterpenes by Gibberella fujikuroi [PDF]

open access: yes, 2004
The incubation of 15B-hydroxy-3-oxo-ent-kaur-16-ene (1) with the fungus Gibberella fujikuroi afforded 11B-hydroxy-3,15-dioxo-ent-kaurane (6), 11B,15B-dihydroxy-3-oxo-ent-kaur-16-ene (8), 7B,11B,15B-trihydroxy-3-oxo-ent-kau-16-ene (9), 7a,11B-dihydroxy-3 ...
Fraga, Braulio M.   +2 more
core  

PTP1B inhibitory activity of kaurane diterpenes isolated fromSiegesbeckia glabrescens

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2006
Protein tyrosine phosphatase 1B (PTP1B) is considered as a therapeutic target for the treatment of diabetes and obesity. In our preliminary screening study, a MeOH extract of the aerial part of Siegesbeckia glabrescens was found to inhibit PTP1B activity at 30 microg/mL.
Sohee, Kim   +7 more
openaire   +2 more sources

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