Lipoxin A4 impairment of apoptotic signaling in macrophages: Implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways [PDF]
El pdf del artículo es la versión pre-print.Lipoxin A4 (LXA4) is an endogenous lipid mediator that requires transcellular metabolic traffic for its synthesis.
Boscá, Lisardo +5 more
core +1 more source
Anticancer diterpenes of African natural products: Mechanistic pathways and preclinical developments [PDF]
64 p.Background: The African continent is home to five biodiversity hotspots, boasting an immense wealth of medicinal flora, fungi and marine life. Diterpenes extracted from such natural products have compelling cytotoxic activities that warrant further ...
Almeida Rosatella, Andreia de +8 more
core +1 more source
Five new ent-kaurane diterpenes from Annona squamosa L. pericarps
In the present study, five new ent-kaurane diterpenes including 4α-hydroxy-17,19-dinor-ent-kaurane-16-one (1), 4β-hydroxy-16β-H-18-nor-ent-kaurane-17-oic acid (2), 4β,17-dihydroxy-16α-acetoxy-18-nor-ent-kaurane (3), Annosquamosin Z (4) and 16α-H-ent-kaurane-17,18-dioic acid, 17-methy ester (5) were isolated from Annona squamosa L. pericarp.
Ya-Yun, Chen +7 more
openaire +2 more sources
Effects of Kaurane Diterpene Derivatives on Germination and Growth of Lactuca sativa Seedlings
Kaurenoic and grandiflorenic acid, isolated from Wedelia paludosa (Asteraceae), some derivatives from these acids (alcohols, esters, amides, lactones, oximes) and other naturally occurring kaurane diterpenes were tested for their action on the growth of radical and shoot of Lactuca sativa.
Henriete S, Vieira +3 more
openaire +2 more sources
Isolation and structural characterization of diterpenoidic compounds and identification of their molecular targets [PDF]
As part of an ongoing research program on plants biosynthesizing diterpenes, it was performed a project aimed to create a diterpenes library from different plant’s species. The attention was paid on plants known to be rich on diterpenes, since they are a
FAIELLA, LAURA
core
The leaves of Mikania laevigata and Mikania glomerata are used in Brazil to treat respiratory affections, being kaurane-type diterpenes and coumarin considered as the bioactive compounds.
SUZAN K.V. BERTOLUCCI +4 more
doaj
Bioactive Ent-Kaurane Diterpenes Oridonin and Irudonin Prevent Cancer Cells Migration by Interacting with the Actin Cytoskeleton Controller Ezrin. [PDF]
Pagliara V +6 more
europepmc +1 more source
Biosynthesis of Diterpenoids in Tripterygium Adventitious Root Cultures [PDF]
Adventitious root cultures were developed from Tripterygium regelii Sprague & Takeda and growth conditions optimized for the abundant production of diterpenoids, which can be collected directly from the medium.
Fischedick, Justin +9 more
core +2 more sources
A Comprehensive Review of the Classification, Sources, Phytochemistry, and Pharmacology of Norditerpenes. [PDF]
Zeng N +6 more
europepmc +1 more source

