Results 211 to 220 of about 129,498 (304)

Optimization of antibody binding by adjusting thermodynamic stability during the maturation of antibody affinities

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Somatic mutations and antibody clone selection occur in B‐cell hyper‐evolution over extremely brief periods of time. Herein, we developed a technique for antibody screening by immunizing alpacas with antigens and observing antibody sequence transitions over time, a method we named Tracking the Evolution of Antibodies over time.
Yoko Akazawa‐Ogawa   +7 more
wiley   +1 more source

Edible Insect Allergens: An Emerging Food Safety Challenge

open access: yesSustainable Food Proteins, Volume 4, Issue 3, September 2026.
Allergic responses to edible insects arise via two main pathways: cross‐reactivity with homologous arthropod allergens and primary sensitization to edible insect proteins, both leading to IgE‐mediated immune activation. ABSTRACT Edible insects are increasingly promoted as sustainable protein sources; however, their allergenic potential remains a ...
Changqi Liu   +5 more
wiley   +1 more source

Contemporary Approaches to Opioid Dependence Treatment Delivery: A Rapid Review of Novel Models Relevant to Implementation in Victoria, Australia

open access: yesDrug and Alcohol Review, Volume 45, Issue 6, September 2026.
ABSTRACT Issues Rising opioid‐related harms and persistent barriers to opioid dependence treatment (ODT) access present critical challenges across Australia and internationally. Pharmacotherapy remains the most effective treatment for opioid use disorder, yet systemic gaps in workforce availability and service models limit reach and sustainability ...
Shalini Arunogiri   +4 more
wiley   +1 more source

Modeling the Histogenetic Switch Between Enameloid and Enamel

open access: yesEvolution &Development, Volume 28, Issue 3, September 2026.
This evo–devo exploration of ~550,000 histogenetic simulations forming dentine, enameloid, and enamel identifies 38 independent ways to induce the enameloid–enamel transition, with delayed matrix vesicle secretion (SVO‐) emerging as the key modification, providing new insights into the origin of enamel in early osteichthyans.
Guillaume Houée   +3 more
wiley   +1 more source

Sex‐ and Age‐Specific Trends in Prescriptions of Beta‐3 Agonists and Anticholinergics in Japan: A Nationwide Prescription Database Study

open access: yesLUTS: Lower Urinary Tract Symptoms, Volume 18, Issue 5, September 2026.
ABSTRACT Introduction To investigate the nationwide trends in pharmacological treatment for overactive bladder among Japanese adults, specifically focusing on the β3‐agonists to anticholinergics prescribed tablet ratio (BAPR) and how this ratio differs by sex and age.
Minato Yokoyama   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy