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Kawasaki disease

Vascular Medicine, 1999
Kawasaki disease is a leading cause of acquired heart disease in children in the USA. An acute vasculitis of unknown etiology, it occurs predominantly in infancy and early childhood, and more rarely in teenagers. Coronary artery aneurysms or ectasia develop in approximately 15-25% of children with the disease. Treatment with intravenous gamma globulin,
J W, Newburger, J C, Burns
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Kawasaki syndrome

Current Opinion in Rheumatology, 1995
Although a general consensus on the etiology of Kawasaki syndrome has not been reached, increasing evidence suggests that this illness represents a response to a superantigen. This conclusion is based on the observations of the immunologic changes that characterize the acute stages of illness as well as on the demonstrated association with toxin ...
H C, Meissner, D Y, Leung
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Kawasaki disease

Current Treatment Options in Cardiovascular Medicine, 2000
Kawasaki disease is an acute vasculitis of unknown cause that occurs predominantly in infants and young children and produces coronary artery aneurysms in approximately 15% to 25% of those affected. In the United States, Kawasaki disease is more commonly the cause of noncongenital heart disease in children than is acute rheumatic fever.
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Kawasaki syndrome'

British Dental Journal, 1989
Kawasaki syndrome is a leading cause of pediatric acquired heart disease in the United States. Coronary artery aneurysms or ectasia develop in approximately 15 to 25 per cent of affected children; treatment with intravenous gamma globulin in the acute phase reduces this risk three- to five-fold.
J W, Newburger, J C, Burns
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Kawasaki Disease

Rheumatic Disease Clinics of North America, 2015
Kawasaki disease (KD) is the archetypal pediatric vasculitis, exemplifying the unique aspects and challenges of vascular inflammation in children. The condition is almost unheard of in adults, is closely associated with infections, and is self-limited, with fever resolving after an average of 12 days even without treatment. Yet KD is also a potentially
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Kawasaki Disease

Pediatric Clinics of North America, 1995
This article is an up-to-date review of issues surrounding Kawasaki disease, with particular emphasis on the immunologic aspects. Kawasaki disease is now the leading cause of acquired heart disease in children in most developed countries.
S T, Shulman, J, De Inocencio, R, Hirsch
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Kawasaki disease

Current Opinion in Rheumatology, 1996
The 5th International Kawasaki Disease Symposium was held in May 1995 in Fukuoka, Japan. No one infectious agent has been found to initiate the syndrome, although the occurrence of Kawasaki disease in epidemics and its resemblance to toxic-shock syndrome make an infectious etiology seem most likely.
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Kawasaki Disease

Pediatric Clinics of North America, 2012
Kawasaki disease is a systemic vasculitis and the leading cause of acquired heart disease in North American and Japanese children. The epidemiology, cause, and clinical characteristics of this disease are reviewed. The diagnostic challenge of Kawasaki disease and its implications for coronary artery outcomes are discussed, as are the recommended ...
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Kawasaki Disease

Pediatrics in Review
Kawasaki disease (KD) is an acute febrile, systemic vasculitis with an unknown etiology that mostly affects children under the age of 5, and it is the most common cause of acquired heart disease in children in developed countries. Despite significant advances in understanding this disease’s pathophysiology, diagnostic methods, and treatment options ...
Katelin, Selmek, Meghan, Harding
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Phase II Open Label Study of Anakinra in Intravenous Immunoglobulin–Resistant Kawasaki Disease

Arthritis & Rheumatology, 2020
Anakinra has been shown to be successful in preventing and treating cardiovascular lesions both in experimental murine models of Kawasaki disease (KD) and in several studies on intravenous immunoglobulin (IVIG)– and steroid‐resistant patients with KD ...
I. Koné-Paut   +13 more
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