Results 21 to 30 of about 115,882 (293)
A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease. [PDF]
, 2009 Kawasaki disease (KD) is a pediatric vasculitis that damages the coronary arteries in 25% of untreated and approximately 5% of treated children. Epidemiologic data suggest that KD is triggered by unidentified infection(s) in genetically susceptible ...Nievergelt, Caroline M., Sundel R.P., Li Y., Ng, S.B., Dillon, M, Shulman, ST, Sarah B Ng, Odam M., Nissan, M, Newburger, Jane W., Shimizu, C, Curtis, Nigel, Jane C Burns, Shike, Hiroko, Bonnard C., Burns, JC, Sundel, Robert P., Dillon, Michael, Bose, A, Kuijpers, Taco W., Burgner, D., Victoria J. Wright, Nissen, Michael, D., Burns Jane C., Shingadia D., Schork, NJ, Witt C., Kuijpers, Taco W, Wright, V.J., Kuipers, IM, Ling, L, Sarah B. Ng, Sonia Davila, Kuijpers, TW, Davila, S, Burgner, David, Ling, L., Odam, M., Breunis, W.B., Bonnard, C., Michie, C, Curtis, N, Ng S.B., Odam, Miranda, Burgner D., Hibberd, ML, Brogan P., Thalamuthu, A., Ziegler, J, Shah, Vanita, Shulman, Stanford T., Wright Victoria J., Ling L., Palasanthiran P., Rowley A.H., Ottenkamp, Jaap J., Breunis W.B., Shah V., Nissan, Michael, Filippini, L, Thalamuthu A., Carine Bonnard, Kuijpers T.W., Tulloh R., Christiansen F., Nourse C., Miranda Odam, Breunis, Willemijn B., Goldwater, P, Filippini L., Klein, Nigel, Biezeveld M., Mukasa, Thomas, Wright, Victoria J, Levin, Michael, Hibberd, M.L., Ng, SB, Curtis N., Thalamuthu, Anbupalam, Li Yi, Nissan M., Kuipers I.M., Rowley, AH, Kuijpers, T.W., Breunis, Willemijn B, Booy R., Dillon M., Rowley, Anne H., Kuipers, Irene M., Levin Michael, Davila, S., Davila Sonia, Booy, Robert, Schork N.J., Nourse, Clare, Li, Y, Shimizu, Chisato, Ng Sarah B., Tulloh, Robert, Consortium, IKDG, Goldwater, Paul, Nievergelt C.M., Bose A., Filippini, Luc, Christiansen, Frank, Li, Y., Ziegler, John, Shulman S.T., Bonnard, C, Geissler J., Burgner David, Willemijn B. Breunis, Ng, Sarah B., Breunis Willemijn B., Martin L Hibberd, Hibberd M.L., Palasanthiran, P, Ling, Ling, Witt, C, Christiansen, F, Breunis, WB, Burns J.C., Shah, V, Burns, Jane C., Hibberd, Martin L., Michie C., Burgner, D, Baker, Annette L., Ottenkamp, JJ, Taco W Kuijpers, Levin, M, Geissler, J, Mukasa, T, Shimizu C., Davila, Sonia, Bose, Anu, Levin, M., Bonnard Carine, Odam Miranda, Nievergelt, CM, Li, Yi, Brugner, David, Jane C. Burns, Davila S., Baker, AL, Ng, Sarah B, Newburger, JW, Baker A.L., Newburger J.W., Willemijn B Breunis, Shike, H, Burns, J.C., Michie, Colin, Biezeveld, Maarten, Hibberd, Martin L, Wright, Victoria J., Biezeveld, M, Levin M., Shingadia, D, Kuijpers Taco W., Martin L. Hibberd, Thalamuthu Anbupalam, Shike H., Wright, VJ, Shimizu Chisato, Ziegler J., Shingadia, Delane, Ottenkamp J.J., Yi Li, Klein N., Geissler, Judy, Burns, Jane C, International Kawasaki Disease Genetics Consortium, Palasanthiran, Pamela, Ling Ling, Taco W. Kuijpers, Wright V.J., Tulloh, R, Bonnard, Carine, Sundel, RP, Shimizu, C., Schork, Nicholas J., Goldwater P., Brogan, P, Mukasa T., Brogan, Paul, Hibberd Martin L., Victoria J Wright, Odam, M, Thalamuthu, A, Witt, Campbell, Michael Levin, David Burgner, Chisato Shimizu, Anbupalam Thalamuthu, Klein, N, Booy, R, Nourse, C +197 morecore +2 more sourcesTNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation
Hepatology, EarlyView., 2022 Abstract Background and Aims
Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara +16 morewiley +1 more sourceMultiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma
Hepatology, EarlyView., 2022 Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims
Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate‐Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara +29 morewiley +1 more sourceAssociation Between Kawasaki Disease and Childhood Epilepsy: A Nationwide Cohort Study in Taiwan
Frontiers in Neurology, 2021 Background: Kawasaki disease is a common vasculitis of childhood in East Asia. The complications following Kawasaki disease mostly included cardiovascular sequelae; non-cardiac complications have been reported but less studied.Chien-Heng Lin, Chien-Heng Lin, Jung-Nien Lai, Jung-Nien Lai, Inn-Chi Lee, I-Ching Chou, I-Ching Chou, Wei-De Lin, Mei-Chen Lin, Mei-Chen Lin, Syuan-Yu Hong +10 moredoaj +1 more sourceReplication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility. [PDF]
, 2013 The BLK and CD40 loci have been associated with Kawasaki disease (KD) in two genome-wide association studies (GWAS) conducted in a Taiwanese population of Han Chinese ancestry (Taiwanese) and in Japanese cohorts.Yi-Min Liu (230875), Lee, Yi-Ching, Jong-Keuk Lee (142576), Chen, Y.-T., Liu, YM, Wu, J.-Y., Lee, Y.-C., Tsai, FJ, Martin L Hibberd, Li-Ching Chang, Taiwan Kawasaki Disease Genetics Consortium, Chang, Chia-Jung, Khor, C.C., Liu, Y.-M., Jane C Burns, Chia-Jung Chang (452299), Ho-Chang Kuo (156547), Li-Ching Chang (230873), Michael Levin (21355), Hibberd, Martin L., Burns, Jane C., Burns, JC, Fuu-Jen Tsai, Gi Young Jang, Chang, J.-S., Burgner, D., Burgner, D, Kuijpers, Taco, Chen, Ying-Ju, Chang, C.-J., Levin, M, Hong, YM, Chen, CH, Davila, Sonia, Wu, JY, Lee, YC, Fuu-Jen Tsai (230856), Chen, Chien-Hsiun, Levin, M., Chien-Hsiun Chen, Chiea Chuen Khor (306345), Jang, G.Y., Sonia Davila, Chen, S.-P., Jong-Keuk Lee, Ko, T.-M., Chen, SP, Burgner, David, Davila, S, Ko, Tai-Ming, Yi-Min Liu, Jane C. Burns (268128), Wu, Jer-Yuarn, Jane C. Burns, Ko, TM, Kuo, HC, Chang, L.-C., Chen, C.-H., Hibberd, ML, Chang, JS, Taco Kuijpers (452304), Lee, Jong-Keuk, Burns, J.C., Jeng-Sheng Chang, Hong, Y.M., Kuijpers, T, Young Mi Hong, Hibberd, Martin L, Yuan-Tsong Chen (19419), Jer-Yuarn Wu (92059), Jang, GY, Kuo, H.-C., Gi Young Jang (452303), Chen, YJ, Liu, Yi-Min, Chang, CJ, Martin L. Hibberd, Ho-Chang Kuo, Chen, Yuan-Tsong, Chen, YT, Tai-Ming Ko, Tai-Ming Ko (452301), Yi-Ching Lee, Chiea Chuen Khor, Chang, Jeng-Sheng, Korean Kawasaki Disease Genetics Consortium, Yi-Ching Lee (214372), Shih-Ping Chen, Burns, Jane C, International Kawasaki Disease Genetics Consortium, Jer-Yuarn Wu, Ying-Ju Chen (296144), Taco Kuijpers, Levin, Michael, Khor, CC, Chang, LC, Hibberd, M.L., Kuijpers, T., Young Mi Hong (452302), Chien-Hsiun Chen (28863), Chen, Y.-J., Sonia Davila (268093), Jang, Gi Young, Yuan-Tsong Chen, Ying-Ju Chen, Chia-Jung Chang, Hong, Young Mi, Chang, Li-Ching, Kuo, Ho-Chang, Lee, J.-K., Khor, Chiea Chuen, Tsai, F.-J., Michael Levin, David Burgner, Davila, S., Tsai, Fuu-Jen, Shih-Ping Chen (452300), Chen, Shih-Ping, Martin L. Hibberd (167212), David Burgner (268086), Lee, JK, Jeng-Sheng Chang (230858) +121 morecore +1 more sourceKawasaki disease [PDF]
, 2017 La enfermedad de Kawasaki es un estado febril agudo, cuya incidencia es de 175
por cada 100.000 ninos ˜ menores de 5 anos. ˜ Es una vasculitis con predilección por los vasos de
pequeno˜ y mediano calibre, especialmente por las arterias coronarias; sin ...Huertas Quiñones, Victor Manuel, Sanguino Lobo, Roy, Ariza Correa, Carolina, Salinas Suárez, Carolina, Matiz Mejía, Sandra +4 morecore +1 more sourceCase report: Cochlear implantation was effective for progressive bilateral severe hearing loss associated with Kawasaki disease
Frontiers in Pediatrics, 2023 Sensorineural hearing loss associated with Kawasaki disease has been increasingly reported, but its etiology remains unclear. Most reported cases of sensorineural hearing loss associated with Kawasaki disease have been mild and reversible during acute or Daichi Murakami, Takahito Kimura, Masamitsu Kono, Akihiro Sakai, Akihiro Sakai, Tomohiro Suenaga, Masanobu Hiraoka, Hideki Sakatani, Makiko Ohtani, Hiroyuki Suzuki, Hiroyuki Suzuki, Daisuke Tokuhara, Muneki Hotomi +12 moredoaj +1 more source
