Results 121 to 130 of about 118,357 (315)

Docetaxel‐Induced Immune Activation Shows Antitumor Synergy With the Tumor‐Targeted CD40 Agonist KK2269

Cancer Science, EarlyView.
CD40 agonists have demonstrated proof‐of‐concept for converting an immunologically cold tumor into a hot tumor in preclinical studies; however, clinically, they have shown limited antitumor efficacy as monotherapy. We tested a tumor‐targeted CD40 agonist, KK2269 (a bispecific antibody that binds to CD40 and EpCAM), in combination with various ...
Yuta Tezuka, Kyoko Kawasaki, Yoshiki Sumitomo, Masato Saito, Akari Yao, Munetoshi Ando   +5 more
wiley   +1 more source

Associations of infection burden with Kawasaki disease in a population-based setting during 30 years

RMD Open
Objectives The objective of this study was to investigate the role of infections in the pathogenesis of Kawasaki disease.Methods The investigation was a nationwide epidemiological case-control study, comprising all cases of Kawasaki disease diagnosed in ...
Johannes Mofors, Håkan Eliasson, Gunnar Bergman, Sven-Erik Sonesson, Marie Wahren-Herlenius, Göran Elinder, André Rudolph, Bodil Schiller   +7 more
doaj   +1 more source

Response to “Acute kidney injury occurs only rarely in patients with Kawasaki disease” [PDF]

, 2017
Gwo‐Tsann Chuang, Luan‐Yin Chang
openalex   +1 more source

Estimated Glomerular Filtration Rate Change and Heart Failure Events With GLP‐1 Receptor Agonists: A Meta‐Analysis and Meta‐Regression of Randomised Controlled Trials

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To examine whether on‐treatment changes in kidney function and cardiometabolic markers are associated with the magnitude of heart failure (HF) risk reduction across large‐scale trials of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs).
Masashi Hasebe, Hisashi Kamido, Chen‐Yang Su, Yamato Keidai, Daisuke Yabe, Satoshi Yoshiji   +5 more
wiley   +1 more source

Reduced Dopamine Transporter Uptake in Dentatorubral‐Pallidoluysian Atrophy

Movement Disorders Clinical Practice, EarlyView.
Kei Okuba, Shugo Fujita, Hitoshi Kawasaki, Genko Oyama   +3 more
wiley   +1 more source

Development of Chimeric Antigen Receptor‐Modified NK Cells for the Immunotherapy of Adult T‐Cell Leukemia/Lymphoma

European Journal of Haematology, EarlyView.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida, Seigo Tateo, Masahiro Wakao, Hiroyuki Shinchi, Hayate Sawayama, Akira Fukumoto, Makoto Yoshimitsu, Yasuo Suda   +7 more
wiley   +1 more source

Utilizing T-Lymphocyte Activation-Related Cytokines to Predict Non-Responsiveness to Treatment in Pediatric Kawasaki Disease

Pediatric Health, Medicine and Therapeutics
Bei Ye,1 Jiying Xiao,2 Caiyun Zhang3 1Department of Pediatrics, Hangzhou Children’s Hospital, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Respiratory Medicine, Hangzhou Children’s Hospital, Hangzhou, Zhejiang, People’s Republic of ...
Ye B, Xiao J, Zhang C
doaj  

A note on the moduli-induced gravitino problem

, 2009
The cosmological moduli problem has been recently reconsidered. Papers [1,2] show that even heavy moduli (m_\phi > 10^5 GeV) can be a problem for cosmology if a branching ratio of the modulus into gravitini is large.
A.A. Starobinsky, D.I. Podolsky, F.Balestra ., J.F. Dufaux, M.Y. Khlopov, N. W. McLachlan, Natalia Shuhmaher   +6 more
core   +1 more source

Prognostic Value of an Early Response to Tolvaptan and Its Clinical Implications in Patients With Cirrhosis and Hepatic Edema: A Nationwide Multicenter Cohort Study

Hepatology Research, EarlyView.
In a nationwide multicenter cohort, an early response to tolvaptan (≥ 1.5‐kg weight loss within 7 days) was independently associated with improved long‐term survival in patients with cirrhosis and hepatic edema. Early initiation before renal impairment or hyponatremia may optimize treatment response and prognosis. ABSTRACT Aim Hepatic edema indicates a
Kaori Koyano, Taeang Arai, Hidenori Toyoda, Keizo Kato, Joji Tani, Suguru Ogura, Tomomi Okubo, Korenobu Hayama, Norio Itokawa, Toshifumi Tada, Akito Nozaki, Atsushi Hiraoka, Kentaro Matsuura, Toru Ishikawa, Naoto Kawabe, Tsunamasa Watanabe, Koichi Takaguchi, Asahiro Morishita, Hironao Okubo, Motoh Iwasa, Hiroki Nishikawa, Yasuhito Tanaka, Masanori Atsukawa   +22 more
wiley   +1 more source

Diagnostic Impact of Two‐Dimensional Shear Wave Elastography for Liver Fibrosis: A Multicenter Retrospective Study

Hepatology Research, EarlyView.
Two‐dimensional shear wave elastography demonstrated strong correlation with magnetic resonance elastography and high diagnostic accuracy for liver fibrosis across stages in 744 patients with chronic liver disease, supporting its role as a reliable non‐invasive tool for fibrosis assessment.
Takashi Nishimura, Toshifumi Tada, Yasuaki Suzuki, Kento Imajo, Katsutoshi Sugimoto, Sadanobu Ogawa, Hidenori Toyoda, Tamami Abe, Hidekatsu Kuroda, Masashi Hirooka, Asako Nogami, Satoshi Oeda, Hirokazu Takahashi, Tomoyuki Akita, Reiichiro Kondo, Takuma Nakatsuka, Ryosuke Tateishi, Yoichi Hiasa, Yuichiro Eguchi, Atsushi Nakajima, Hirohisa Yano, Shigehiro Kokubu, Junko Tanaka, Fuminori Moriyasu, Masayoshi Kage, Takashi Kumada, Hiroko Iijima   +26 more
wiley   +1 more source