Results 81 to 90 of about 36,113 (205)

Five‐Year Unified Risk Prediction Model for Gastric and Esophageal Cancer Based on Nationwide Health Check‐Up Data in Japan: J‐GESS Score

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim In Japan, gastric cancer (GC) and esophageal squamous cell carcinoma (ESCC) account for nearly all fatal upper gastrointestinal malignancies. A unified model that simultaneously predicts the incidence of these two cancers could help optimize endoscopic screening and postindex surveillance strategies.
Kenta Watanabe, Sho Fukuda, Dai Kubota, Nobutake Yamamichi, Yu Takahashi, Yoshitaka Watanabe, Kyoichi Adachi, Norihisa Ishimura, Tomoyuki Koike, Hideyuki Sugawara, Kiyotaka Asanuma, Yasuhiko Abe, Takashi Kon, Eikichi Ihara, Kazuhiro Haraguchi, Yoshihiro Otsuka, Rie Yoshimura, Yugo Iwaya, Takuma Okamura, Noriaki Manabe, Akira Horiuchi, Mio Matsumoto, Kengo Onochi, So Takahashi, Tatsuki Yoshida, Yosuke Shimodaira, Katsunori Iijima   +26 more
wiley   +1 more source

Development of Multidisciplinary Consensus‐Informed Guidance for the Management of Paediatric Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Among Clinicians From Australasian Tertiary Referral Hospitals

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Paediatric Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, severe mucocutaneous reaction requiring coordinated multidisciplinary care. Existing guidelines provide evidence‐based recommendations, but implementation across tertiary paediatric hospitals requires practical consensus on local resources.
Patrick David Mahar, Thomas Lee, David Orchard, Amy Gray, Laura Scardamaglia, Susan Robertson, Monique Bertinetti, Warwick Teague, Danielle Nizzero, Claire Grills, Ryan Toholka, Danni Bao, Julian Kelly, Joanne Grindlay, Thomas Rozen, Mark Oliver, Nicole Alexander, Ashan Fernando, Anu Matthew, Kiri Chan, Sonia R. Grover, Emma McDonald, Li‐Chuen Wong, Marius Rademaker, Diana Purvis, Katherine Dear, Stephanie Weston, Vanessa Morgan, Anne Halbert, Orli Wargon, Gayle Fischer, Erin Mewton, Emma King   +32 more
wiley   +1 more source

Prevalence, Comparative Risk, and Predictors of Shock in Children With Multisystem Inflammatory Syndrome Associated With COVID‐19: A Systematic Review and Meta‐Analysis

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Multisystem inflammatory syndrome in children (MIS‐C) is a severe hyperinflammatory condition associated with SARS‐CoV‐2 infection and is frequently complicated by cardiovascular dysfunction, particularly shock. Early recognition of shock in MIS‐C is critical to reduce morbidity and mortality.
Asif Jan, Bushra Waheed, Ghadah Ali Hussein, Pratima Pandey, Huma Sultana, Shubham Kumar, Mequanente Dagnaw   +6 more
wiley   +1 more source

Unveiling Potato Cultivars With Microbiome Interactive Traits for Sustainable Agricultural Production

Plant, Cell &Environment, EarlyView.
ABSTRACT Root traits significantly shape rhizosphere microbiomes, yet their interaction with microbes is often overlooked in plant breeding programs. Here, we propose that selecting modern cultivars based on microbiome interactive trait (MIT), such as root biomass, exudate patterns and the rhizosphere microbiome, can enhance agricultural sustainability
Tianci Zhao, Stefanie N. Vink, Xiu Jia, Alexander Erban, Stephanie Schaarschmidt, Joachim Kopka, Ellen Zuther, Krzysztof Treder, Dorota Michałowska, Rémy Guyoneaud, J. Theo M. Elzenga, Eléonore Attard, Joana Falcão Salles   +12 more
wiley   +1 more source

Optimising the workflow for infant ABO blood typing: The role of automated analyser and a manual reflex protocol

Transfusion Medicine, EarlyView.
Abstract Objectives We aimed to optimise the infant ABO typing workflow by evaluating the performance of the ORTHO VISION analyser (VISION; QuidelOrtho, San Diego, CA, USA) and establishing a targeted manual reflex protocol. Background The application of automated analysers in infants poses challenges due to weak antigen and antibody expression ...
Eunhui Ji, Seung Hwan Oh, Sun Min Lee, In‐Suk Kim, Hyun Ji Lee   +4 more
wiley   +1 more source

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance

Experimental Physiology, EarlyView.
Abstract Passive hyperthermia increases net peripheral and systemic blood flow in humans and other animals, yet the underlying haemodynamic forces that selectively accelerate blood movement remain incompletely characterized. Wave intensity analysis offers insight into the respective contributions of the heart and the vascular system to changes in blood
Nuno Koch Esteves, Kazuhito Watanabe, Francesca R. Cavallo, Ashraf W. Khir, José González‐Alonso   +4 more
wiley   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

MCT1‐mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell‐derived barrier model

The Journal of Physiology, EarlyView.
Abstract figure legend Propionate in the fetal circulation is thought to originate from fermentation of dietary fibre by the maternal gut microbiota. However, the mechanism of transplacental transport has remained unclear. Here, we measured propionate permeability using a placental barrier model generated by differentiating human placental trophoblast ...
Toshiaki Tsuchitani, Rin Midorikawa, Akari Kasuya, Saki Noguchi, Kohei Yamamoto, Tomohiro Nishimura, Hirokazu Kaji, Takeshi Hori, Masatoshi Tomi   +8 more
wiley   +1 more source

Kawasaki disease shock syndrome: a severe form of Kawasaki disease

The Turkish Journal of Pediatrics, 2013
Kawasaki disease is a systemic vasculitis, primarily encountered in children. Its clinical presentation is well known, and coronary artery abnormalities are classical complications. Shock is not a common form of presentation of the disease.
Rana İşgüder, Önder Doksöz, Özlem Bağ, Hasan Ağın, Timur Meşe, Ünal Utku Karaarslan, İlker Devrim   +6 more
doaj