Results 61 to 70 of about 1,474 (144)
Sublethal salinity stress contributes to habitat limitation in an endangered estuarine fish. [PDF]
, 2016 As global change alters multiple environmental conditions, predicting species' responses can be challenging without understanding how each environmental factor influences organismal performance.
Connon, Richard E +6 more
core +1 more source
Transcriptomic analysis of fetal membranes reveals pathways involved in preterm birth
BMC Medical Genomics, 2019 Background Preterm birth (PTB), defined as infant delivery before 37 weeks of completed gestation, results from the interaction of both genetic and environmental components and constitutes a complex multifactorial syndrome.
Silvana Pereyra +3 more
doaj +1 more source
Memory T Cells Specific for Murine Cytomegalovirus Re-Emerge after Multiple Challenges and Recapitulate Immunity in Various Adoptive Transfer Scenarios. [PDF]
, 2015 Reconstitution of CMV-specific immunity after transplant remains a primary clinical objective to prevent CMV disease, and adoptive immunotherapy of CMV-specific T cells can be an effective therapeutic approach.
Deslouches, Berthony +5 more
core +2 more sources
Advanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.A simplified, co‐culture‐free protocol for kidney organoids that generate segmented nephrons, including collecting ducts, has been developed. Early low‐dose RA with FGF9 induces balanced anterior–posterior IM patterning and dual UE/MM lineage commitment. BMP7 enhances nephron progenitor maturation.
Jung Hwa Lim +13 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +86 more
wiley +1 more source
Acute and Chronic Respiratory Effects from Repeated Audiogenic Seizures in SS Kcnj16−/− Rats
The FASEB Journal, 2018 Kir5.1 is a member of an inwardly rectifying potassium (Kir) channel family highly expressed in the kidney and brain. Mutations in ion channel genes can alter neuronal excitability, and mutations in related Kir genes have been linked to seizure disorders in humans. We previously established that a knockout rat model of
Anna D. Manis +5 more
openaire +1 more source
Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.HBV DNA integrates in multiple genes including KMT2B in pancreatic cancer. KMT2B upregulation caused by HBV integration or other mechanisms promotes FYN expression via histone H3K4 trimethylation at its promoter region. Increased FYN expression activates the PI3K/Akt signalling pathway, thus driving PDAC cell proliferation, migration and invasion ...
Mengge Li +16 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 4, Page 3028-3041, August 2025.Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome accounting for half of heart failure cases. Although natriuretic peptides are the most accepted and extensively used biomarkers for heart failure, their diagnostic accuracy for HFpEF remains debatable.
Reza Parvan +8 more
wiley +1 more source
Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]
, 2010 Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Dimitris Anastassiou +3 more
core +1 more source
The emerging role of the inwardly rectifying K+ channels in autism spectrum disorders and epilepsy [PDF]
, 2011 Autism is a complex behavioral disorder that develops prior to age three years and is distinguished by high heritability. Many genes predisposing to autism spectrum disorders (ASDs) have been identified.
D’Adamo, Maria Cristina +7 more
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