Results 161 to 170 of about 23,687 (206)

Development of a multiplex SNaPshot assay for simultaneous detection of multiple insecticide-resistance mutations in Anopheles sinensis. [PDF]

Parasit Vectors
Xin Y, Yue Z, Yan S, Yu C, Liu M, Yang S, Xie R, Zheng B, Yin J, Xu B.   +9 more
europepmc   +1 more source

<i>Lycium barbarum</i> Polysaccharide and Chlorogenic Acid Ameliorate LPS-Induced Acute Lung Injury via the NF-κB Signaling Mediated Multi-Targets. [PDF]

Food Sci Nutr
Wang Z, Hao J, Yin J, Rao H, Zhao X, Yu L, Zhao D.   +6 more
europepmc   +1 more source

Insulin Resistance is Associated With Skin Microvascular Dysfunction and Reduced Circulating Endothelial Progenitor Cells in Hypertensive Patients. [PDF]

J Clin Hypertens (Greenwich)
Lu YW, Chang CC, Chou RH, Kuo CS, Tsai SH, Huang PH.   +5 more
europepmc   +1 more source

The expression of phosphorylated KDR in haematological malignancies

, 2016
Pillai, G, Zhang, Y, Blasquez, C, Cook, N, Bianchi, F, Turley, H, Leek, R, Pezzella, F, Watt, S, Gatter, K   +9 more
openaire   +1 more source

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Thienopyridine urea inhibitors of KDR kinase

Bioorganic and Medicinal Chemistry Letters, 2007
A series of substituted thienopyridine ureas was prepared and evaluated for enzymatic and cellular inhibition of KDR kinase activity. Several of these analogs, such as 2, are potent inhibitors of KDR (
George A Cunha, Patrick A Marcotte, Lori J Pease   +2 more
exaly   +4 more sources

Isoindolinone ureas: a novel class of KDR kinase inhibitors

Bioorganic and Medicinal Chemistry Letters, 2004
A series of substituted isoindolinone ureas was prepared and evaluated for enzymatic and cellular inhibition of KDR kinase activity. Several of these analogs, such as 14c, are potent inhibitors of KDR both enzymatically (< 50 nM) and cellularly < or = 100 nM).
Michael L Curtin, George A Cunha, Lori J Pease   +2 more
exaly   +3 more sources

Frequency of kdr Gene in House Fly Field Populations: Correlation of Pyrethroid Resistance and kdr Frequency

Journal of Economic Entomology, 2004
The frequency of the L1014 F kdr mutation was determined in 14 field populations of house flies, Musca domestica L., with resistance factors at LD50 for pyrethrin/piperonyl butoxide and bioresmethrin/piperonyl butoxide from 4 to 29 and 2 to 98, respectively. A polymerase chain reaction test for identifying kdr homo- or heterozygote house flies was used
Huang, J., Kristensen, Michael; id_orcid 0000-0001-7332-3490, Qiao, C.-L., Jespersen, Jørgen Brøchner   +3 more
openaire   +3 more sources

KDR genetic predictor of toxicities induced by sorafenib and regorafenib

The Pharmacogenomics Journal, 2022
No biomarkers are available to predict toxicities induced by VEGFR TKIs. This study aimed to identify markers of toxicities induced by these drugs using a discovery-validation approach. The discovery set included 140 sorafenib-treated cancer patients (TARGET study) genotyped for SNPs in 56 genes.
Quintanilha, Julia C F, Geyer, Susan, Etheridge, Amy S, Racioppi, Alessandro, Hammond, Kelli, Crona, Daniel J, Peña, Carol E, Jacobson, Sawyer B, Marmorino, Federica, Rossini, Daniele, Cremolini, Chiara, Sanoff, Hanna K, Abou-Alfa, Ghassan K, Innocenti, Federico   +13 more
openaire   +2 more sources