Results 171 to 180 of about 9,255 (204)

Development of a multiplex SNaPshot assay for simultaneous detection of multiple insecticide-resistance mutations in Anopheles sinensis. [PDF]

Parasit Vectors
Xin Y, Yue Z, Yan S, Yu C, Liu M, Yang S, Xie R, Zheng B, Yin J, Xu B.   +9 more
europepmc   +1 more source

The kdr mutation occurs in the Mopti form of Anopheles gambiaes.s. through introgression

Insect Molecular Biology, 2000
International audienceAnopheles gambiae s.s. is a complex of sibling taxa characterized by various paracentric inversions. In west and central Africa, where several taxa are sympatric, a kdr mutation responsible for pyrethroid resistance has been ...
Mylene Weill, Fabrice Chandré, Sylvie Manguin   +2 more
exaly   +2 more sources

Functional analysis of a rat sodium channel carrying a mutation for insect knock-down resistance (kdr) to pyrethroids

FEBS Letters, 1997
Pyrethroid insensitivity in resistant (kdr) insects has been correlated with a leucine to phenylalanine replacement in the S6 transmembrane segment of domainII of the axonal sodium channel α(para)-subunit.
Martin S Williamson, Alan L Devonshire
exaly   +2 more sources

Distribution of pyrethroid and DDT resistance and the L1014F kdr mutation in Anopheles gambiae s.l. from Burkina Faso (West Africa)

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009
The study reports on the distribution of pyrethroid and DDT resistance and the L1014F knockdown resistance (kdr) mutation in Anopheles gambiae s.l. populations from 21 localities in three different climatic zones of Burkina Faso from August to October ...
K R Dabire, A Diabate, Chris Bass
exaly   +2 more sources

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Insecticide susceptibility and detection of kdr-gene mutations in Aedes aegypti of Peshawar, Pakistan

Acta Tropica, 2023
Dengue is an endemic disease in Peshawar, Pakistan and its primary vector is Aedes aegypti mosquito. Due to absence of vaccines and proper treatment for dengue, vector control becomes a necessary tool for disease management. Reported insecticide resistance in vectors is a serious threat to the control of dengue.
Gule, Tanzila, Syed Basit, Rasheed, Nazma Habib, Khan, Aisha, Kausar, Fatima, Jahan, Sobia, Wahid   +5 more
openaire   +2 more sources

Abstract 73: Targeting KDR mutations in lung adenocarcinoma

Cancer Research, 2015
Abstract KDR, also known as VEGFR2, is a target of several VEGFR inhibitors, however, only bevacizumab, which targets the VEGF ligand, is FDA approved for lung cancer. Since an activating mutation in KDR was identified in 70% of lung adenocarcinoma patients we sought to identify the number of available clinical trials targeting KDR in ...
Susan M. Mockus, Christopher S. Potter, Grace A. Stafford, Guruprasad Ananda, Douglas Hinerfeld, Gregory J. Tsongalis   +5 more
openaire   +1 more source

Widespread resistance of pollen beetles to pyrethroids in Czechia with no evidence for kdr mutation

Crop Protection, 2021
Abstract The pollen beetle Brassicogethes aeneus (Fabricius, 1775) (Coleoptera: Nitidulidae) is one of the most important pests in oilseed rape (Brassica napus L. var. oleifera Moench) in Czechia. Wide-spread resistance development to pyrethroids in pollen beetle populations was documented in many European countries, including Czechia.
Tomáš Hovorka, František Kocourek, Tereza Horská, Jitka Stará   +3 more
openaire   +1 more source

First report of L1014F kdr mutation inCulex quinquefasciatusin Mexico

Insect Science, 2015
AbstractThe L1014F mutation in the voltage‐sodium channel gene has been associated with resistance to DDT and pyrethroids in various arthropod species including mosquitoes. We determined the frequency of the L1014F kdr mutation in 16 field populations ofCulex quinquefasciatusfrom Northeastern Mexico collected between 2008 and 2013.
Gustavo, Ponce, Iram P, Sanchez, Selene M, García, Jose M, Torrado, Saúl, Lozano-Fuentes, Beatriz, Lopez-Monroy, Adriana E, Flores   +6 more
openaire   +2 more sources

Toxicological and molecular characterization of pyrethroid-resistant horn flies, Haematobia irritans: identification of kdr and super-kdr point mutations

Insect Biochemistry and Molecular Biology, 1997
Two pyrethroid-resistant strains of horn flies were found to be 17- and 688-fold more resistant to permethrin and 17- and 11,300-fold more resistant to cyhalothrin than a susceptible control strain. Synergism experiments with piperonyl butoxide showed that both target site insensitivity and metabolic resistance mechanisms were present in the Super ...
F D, Guerrero, R C, Jamroz, D, Kammlah, S E, Kunz   +3 more
openaire   +2 more sources

kdr: can a single mutation produce an entire insecticide resistance phenotype?

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2008
Knockdown resistance (kdr) is closely associated with DDT and pyrethroid resistance in the major malaria vector Anopheles gambiae and is considered to be causative of the resistance phenotype. The same association does not apply to Sudanese populations of the closely related malaria vector A. arabiensis.
Basil D Brooke, Brooke Basil D
exaly   +3 more sources