Results 31 to 40 of about 544,512 (208)

KDR Activating Mutations in Human Angiosarcomas Are Sensitive to Specific Kinase Inhibitors [PDF]

Cancer Research, 2009
Abstract Angiosarcomas (AS) represent a heterogeneous group of malignant vascular tumors occurring not only in different anatomic locations but also in distinct clinical settings, such as radiation or associated chronic lymphedema. Although representing only 1% to 2% of soft tissue sarcomas, vascular sarcomas provide unique insight into ...
Cristina R, Antonescu, Akihiko, Yoshida, Tianhuo, Guo, Ning-En, Chang, Lei, Zhang, Narasimhan P, Agaram, Li-Xuan, Qin, Murray F, Brennan, Samuel, Singer, Robert G, Maki   +9 more
openaire   +2 more sources

Evidence of increasing Leu-Phe knockdown resistance mutation in Anopheles gambiae from Niger following a nationwide long-lasting insecticide-treated nets implementation

Malaria Journal, 2008
Background At the end of 2005, a nationwide long-lasting insecticide-treated net (LLIN) distribution targeting the most vulnerable populations was implemented throughout Niger. A large number of studies in Africa have reported the existence of anopheline
Duchemin Jean-Bernard, Arzika Ibrahim, Labbo Rabiou, Czeher Cyrille   +3 more
doaj   +1 more source

A pre-intervention study of malaria vector abundance in Rio Muni, Equatorial Guinea: their role in malaria transmission and the incidence of insecticide resistance alleles. [PDF]

, 2008
BACKGROUND: Following the success of the malaria control intervention on the island of Bioko, malaria control by the use of indoor residual spraying (IRS) and long-lasting insecticide-treated nets (LLITN) was extended to Rio Muni, on the mainland part of
Mohloai, P., Govender Dayanandan, Ramdeen, Varsha, Kleinschmidt, Immo, Ramdeen Varsha, Bass, C. G., Schwabe, C, Govender, D, Ramdeen, V., Kleinschmidt, I., Edu Amado, Govender, D., Edu, Amado Edjang, Mohloai, Peter, Kleinschmidt Immo, Bass, Chris, Yellot Lee, Edu, AE, Bass, C, Maharaj, R, Yellot, Lee, Ridl Frances C, Schwabe Christopher, Maharaj, Rajendra, Torrez, M, Ramdeen, V, Mohloai, P, Schwabe, C., Ridl, Frances C, Torrez Miguel, Ridl, F. C., Ridl, FC, Torrez, Miguel, Maharaj, R., Yellot, L., Mohloai Peter, Govender, Dayanandan, Torrez, M., Edu, A. E., Schwabe, Christopher, Yellot, L, Bass Chris, Maharaj Rajendra, Kleinschmidt, I   +43 more
core   +1 more source

F1534S <i>kdr</i> mutation drives the geographical heterogeneity of pyrethroid resistance in <i>Aedes albopictus</i> from Hangzhou, China. [PDF]

Front Cell Infect Microbiol
IntroductionThe rapid evolution of insecticide resistance in mosquitoes has substantially compromised control efficacy against Aedes albopictus. This study aimed to evaluate the resistance levels to commonly used insecticides in field populations of Ae ...
Jin B, Du J, Wei L, Duan T, Xu J, Wang Y, Lu Y, Jin H.   +7 more
europepmc   +2 more sources

Functional analysis of a rat sodium channel carrying a mutation for insect knock-down resistance (kdr) to pyrethroids [PDF]

, 1997
Pyrethroid insensitivity in resistant (kdr) insects has been correlated with a leucine to phenylalanine replacement in the S6 transmembrane segment of domainII of the axonal sodium channel α(para)-subunit.
Eldursi, N., Devonshire, A.L, Vais, H, Usherwood, P.N.R, H Vais, P.N.R Usherwood, Hick, C.A, Eldursi, N, C.A Hick, N Eldursi, Devonshire, A. L., M.S Williamson, Vais, H., Usherwood, P. N. R., Hick, C. A., A.L Devonshire, Williamson, M.S, Williamson, M. S.   +17 more
core   +1 more source

Mutation testing on an object-oriented framework: An experience report [PDF]

, 2011
This is the preprint version of the article - Copyright @ 2011 ElsevierContext The increasing presence of Object-Oriented (OO) programs in industrial systems is progressively drawing the attention of mutation researchers toward this paradigm.
Sergio Segura, Segura, S, Benavides, D, Antonio Ruiz-Cortés, Ruiz Cortés, Antonio, Segura Rueda, Sergio, Robert M. Hierons, Benavides Cuevas, David Felipe, Hierons, Robert M., David Benavides, Hierons, RM, Ruiz-Cortes, A   +11 more
core   +1 more source

Molecular forms of the Indian Anopheles subpictus complex differ in their susceptibility to insecticides and the presence of knockdown resistance (kdr) mutations in the voltage-gated sodium channel.

PLoS ONE, 2023
ObjectivesTo investigate the differential insecticide-susceptibility of two molecular forms of Anopheles subpictus complex (A and B) against DDT and pyrethroids, the occurrence of knockdown resistance (kdr) mutations in these forms, and the association ...
Ankita Sindhania, Himanshu P Lohani, Madhavinadha Prasad Kona, Taranjeet Kaur, B R Kaushal, Om P Singh   +5 more
doaj   +1 more source

Knockdown resistance mutations distribution and characteristics of Aedes albopictus field populations within eleven dengue local epidemic provinces in China

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundAedes albopictus, commonly known as the tiger mosquito, has attracted global attention because its bite can transmit several viruses, such as dengue virus.
Chunchun Zhao, Xinxin Zhou, Xinxin Zhou, Chuizhao Xue, Xinchang Lun, Wenyu Li, Xiaobo Liu, Haixia Wu, Xiuping Song, Jun Wang, Qiyong Liu, Fengxia Meng   +11 more
doaj   +1 more source

Modifications of pyrethroid effects associated with kdr mutation in Anopheles gambiae

Medical and Veterinary Entomology, 2000
Summary Effects of knockdown resistance ( kdr ) were investigated in three pyrethroid‐resistant (RR) strains of the Afrotropical mosquito Anopheles gambiae Giles (Diptera: Culicidae): Kou from Burkina Faso, Tola and Yao from Côte d ...
/Chandre, Fabrice, /Darriet, Frédéric, Duchon, S., /Finot, Luc, /Manguin, Sylvie, /Carnevale, Pierre, /Guillet, Pierre   +6 more
openaire   +3 more sources

Reduced efficacy of insecticide-treated nets and indoor residual spraying for malaria control in pyrethroid resistance area, Benin. [PDF]

, 2007
The pyrethroid knockdown resistance gene (kdr) has become widespread in Anopheles gambiae in West Africa. A trial to test the continuing efficacy of insecticide-treated nets (ITN) and indoor residual spraying (IRS) was undertaken in experimental huts at ...
Mark Rowland, Rowland, Mark, N'Guessan, Raphael, Akogbéto, Martin, Vincent Corbel, Corbel, Vincent, Raphael N’Guessan, Martin Akogbéto   +7 more
core   +1 more source