Results 141 to 150 of about 28,056 (199)

Lipidomic Analysis of Plasma Extracellular Vesicles from Adiponectin Deficient Mice or Metabolic Syndrome Patients Reveals Pro‐Oxidative and Pro‐Inflammatory Lipid Signatures Correlating with Metabolic Dysfunction

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Adiponectin deficiency remodels the lipid composition of plasma extracellular vesicles (EV), enriching polyunsaturated phospholipids and reducing lysophospholipids. These remodelled EV impact oxidative, inflammatory and metabolic function in recipient cells.
Sungji Cho   +13 more
wiley   +1 more source

Agreement Between the Harmonized and the Self‐Explanatory Versions of the Revised ALS Functional Rating Scale in a Clinical Setting

open access: yesMuscle &Nerve, Volume 73, Issue 2, Page 250-259, February 2026.
ABSTRACT Introduction/Aims The harmonized version of the ALS Functional Rating Scale ‐ Revised (ALSFRS‐R) is typically administered according to standard operating procedures (SOPs) to ensure procedural consistency. In contrast, obtaining the self‐explanatory (SE) version of the ALSFRS‐R does not include the use of SOPs.
André Maier   +11 more
wiley   +1 more source

Adaptive Seamless Phase II/III Randomization Test Considering Treatment Group Selection Based on Short–Term Binary Outcomes

open access: yesStatistics in Medicine, Volume 45, Issue 3-5, -Not available-.
ABSTRACT Recently, adaptive seamless phase II/III designs (ASDs) have gained attention because they improve the efficiency of drug development. In an ASD, a phase II trial, which explores the dose–response relationships and identifies treatments for the phase III trial, is combined with a phase III trial, which aims to demonstrate the efficacy and ...
Funato Sato   +4 more
wiley   +1 more source

Tectonics as a Regulator of Shoreline Retreat and Rocky Coast Evolution Across Timescales

open access: yesAGU Advances, Volume 7, Issue 1, February 2026.
Abstract Rocky coast morphology is shaped by interactions between wave action, sea level, and tectonics over millennial time scales. However, a clear and quantifiable signature of tectonic uplift on decadal to centennial shoreline retreat rates is outstanding.
Cesar G. Lopez, Claire C. Masteller
wiley   +1 more source

Carbon Cycle Succession Across a Permafrost Thaw Gradient in Northeastern Alberta as Revealed by δ13C in Dissolved Solids, Gases, and Particulates in Lakes

open access: yesJournal of Geophysical Research: Biogeosciences, Volume 131, Issue 2, February 2026.
Abstract δ13C in particulate organic carbon (POC), dissolved organic carbon (DOC), dissolved inorganic carbon (DIC), carbon dioxide (CO2(g)) and methane (CH4(g)), together with geochemical modeling, were applied to describe carbon cycle evolution in 40 boreal lakes situated across a permafrost thaw gradient in northeastern Alberta, Canada, where ...
J. J. Gibson, P. Eby, A. Jaggi
wiley   +1 more source

Addressing Known Challenges in Solar Flare Forecasting I: Limb‐Flare Prediction With a 4π Full‐Heliosphere Framework

open access: yesSpace Weather, Volume 24, Issue 2, February 2026.
Abstract A demonstrated failure mode for operational solar flare forecasting is the inability to forecast flares that occur near, or just beyond, the solar limb. To address this shortcoming, we develop a “4π $4{\uppi }$” full‐heliosphere event forecasting framework and evaluate its statistical classification ability against this specific challenge.
K. D. Leka   +5 more
wiley   +1 more source

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