Results 251 to 260 of about 10,616 (265)

Tau protein liquid–liquid phase separation can initiate tau aggregation

EMBO Journal, 2018
Susanne Wegmann, Bahareh Eftekharzadeh, Katharina Tepper   +2 more
exaly  

Roles of tau protein in health and disease

Acta Neuropathologica, 2017
Tong Guo, Wendy Noble, Diane P Hanger
exaly  

Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brains

Acta Neuropathologica, 2014
Michiyo Iba, Bin Zhang, Virginia M -Y Lee   +2 more
exaly  

Tau-based therapies in neurodegeneration: opportunities and challenges

Nature Reviews Drug Discovery, 2017
Chuanzhou Li, Jürgen Gotz, Gotz Jürgen   +2 more
exaly  

18 F‐AV‐1451 and CSF T‐tau and P‐tau as biomarkers in Alzheimer's disease

EMBO Molecular Medicine, 2017
Niklas Mattsson, Michael Scholl, Olof Strandberg   +2 more
exaly  

Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

Nature Reviews Drug Discovery, 2009
Kurt R Brunden, John Q Trojanowski, Virginia M -Y Lee   +2 more
exaly  

Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer‘s disease

Brain, 2014
Bernd Bohrmann, Laurence Özmen
exaly  

Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC’s afferent and efferent connections

Acta Neuropathologica, 2015
Michiyo Iba, Jennifer D Mcbride, Jing L Guo   +2 more
exaly  

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

Proceedings of the National Academy of Sciences of the United States of America, 2015
Harindranath Kadavath, Jacek Biernat, Katharina Tepper   +2 more
exaly  

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

Brain, 2015
Nicole M Maphis, Guixiang Xu, Olga N Kokiko-Cochran   +2 more
exaly