Results 21 to 30 of about 12,886 (205)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Müze Eğitimi ve Uygulamaları Dersini Geliştirmeye Yönelik Bir Eylem Araştırması: ‘Bir Kenti Anlamak’

open access: yesAnadolu Üniversitesi Eğitim Fakültesi dergisi, 2022
Yaşamın her alanında olduğu gibi günümüz sanat eğitimini de şekillendiren postmodernist bakış, sanat eğitimini alışılmış uygulamaların dışına çıkmaya teşvik etmektedir.
Kibar Evren Bolat
doaj  

On the Discovery of a Late Acheulean 'Giant' Handaxe from the Maritime Academy, Frindsbury, Kent

open access: yesInternet Archaeology, 2023
This article presents initial results from excavations at Maritime Academy, Frindsbury, which produced several handaxes, two of which can be classed as 'giant handaxes'.
Letty Ingrey   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Sanat Bağlamında Gündelik Hayatın Eleştirisi ve Sokak Sanatı

open access: yesBodrum Journal of Art and Design, 2022
Sosyolojide olduğu gibi sanat alanında da “gündelik hayat ve eleştirisi” her zaman önemli konulardan biri olmuştur. Öyle ki; sanat tarihi boyunca gündelik hayatın farklı şekillerde sanata konu edildiğini gözlemlemek mümkündür.
Esma Burcu Havası , Kaan Canduran
doaj  

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Sakarya’da Sosyal Yaşamın Dönüşümü

open access: yesİletişim Kuram ve Araştırma Dergisi, 2021
Ankara’da Sakarya olarak anılan bölge kentin merkezinde bulunması nedeniyle kentlilerin yoğun biçimde kullandığı mekânlarından biri olagelmiştir. Bu nedenle günümüze kadar sosyal yaşamın bir alanı olarak varlığını sürdürmekte ve hem kentin hem de ...
Özgün Dinçer
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Clinical Validation of Artificial Intelligence (AI)‐based Cartilage Segmentation Predicting Knee Replacement

open access: yesArthritis Care &Research, Accepted Article.
Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein   +3 more
wiley   +1 more source

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