Results 111 to 120 of about 430,959 (308)

Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis

open access: yesAngewandte Chemie, EarlyView.
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood   +6 more
wiley   +2 more sources

Immigrant mental health, safe work, discrimination, and state policies: From racism and xenophobia to health equity

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract An ecological model was developed to examine the pathways linking immigration state policies to physically safe work conditions and work volition, interpersonal discrimination, and mental health distress. The ecological framework was tested among two subsamples totaling 529 Latinx immigrant participants: (1) immigrants who resided in states ...
Germán A. Cadenas   +6 more
wiley   +1 more source

Rerouting Oxygen Evolution Through Interfacial Carbonate Chemistry in Near‐Neutral Seawater Electrolysis

open access: yesAngewandte Chemie, EarlyView.
Carbonate species play a previously overlooked role in near‐neutral seawater electrocatalysis. By coupling electrochemical hydrodynamics with mesoscopic simulations, we reveal a plausible carbonate‐mediated route in which carbonate functions as an interfacial proton acceptor and water as the oxygen donor, showing a possible mechanistic picture of ...
Miao Wang   +2 more
wiley   +2 more sources

Limited Agreement Between Perceptual and Physiological Heat Strain at Initial Stay Times for Continuous Work in the Heat Before Heat Alleviation Controls

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction Accurate assessment of heat strain at initial stay time (IST; core temperature 38.0°C or Δ1.0°C above resting), when heat mitigation decisions are required, is critical for managing occupational heat exposure. We evaluated the relationship and agreement between physiological (Physiological Strain Index [PSI] and adaptive PSI [aPSI]
Gil Bourgois   +4 more
wiley   +1 more source

The Kent Historian, Kent Historical Society Newsletter, Number 85, Summer 2015

open access: yes, 2015
THE KENT HISTORIAN The Newsletter of the Kent Historical Society Summer 2015 Number85 Campaign seeks to bring Kent history to the world Funds would allow digitization of newspapers from early 1900s Newspapers are fragile.

core  

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

open access: yesAngewandte Chemie, EarlyView.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster   +13 more
wiley   +2 more sources

Timing of Work‐Rest Implementation Influences Worker Productivity Under Heat Stress: Evidence for Initial Stay Time‐Based Scheduling

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction Work‐rest allocations recommended by the American Conference of Governmental Industrial Hygienists (ACGIH) limit heat strain and are typically implemented from the onset of work. Whether delaying implementation until after the initial stay time (IST; the duration of continuous work before core temperature reaches 38.0°C) improves ...
Glen P. Kenny   +6 more
wiley   +1 more source

Kent Arşivi Kültürü İhtiyacımız

open access: yesTürk Kütüphaneciliği, 2016
Kentler; kendi sınırları ve bu sınırlar içerisinde kendi normatif değerleri ile inançları olan ve belirli sosyal ilişkiler sistemiyle oluşmuş yerleşim yerleridir.
Yasin Şeşen
doaj  

KENT TURİZMİNİN MARKA KENT OLUŞUMUNDAKİ ETKİSİ: ÇANAKKALE KENT TURİZMİNİN SWOT ANALİZİ

open access: yesYüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2019
Günümüzde çevrede meydana gelen değişim, insanların yaşam ve davranışları üzerinde önemli etkiler oluşturmaktadır. Yaşanan bu değişiklikler ile insanlar farklı kentlere gidip yeni deneyimler kazanmak istemişlerdir. Dar kalıplara sığdırılmış turizmin çevre, yerli halk ve ziyaretçiler arasında etkileşimini uzun bir süreye yaymak için farklı turizm ...
TEMİZ, Merve   +4 more
openaire   +3 more sources

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