Results 101 to 110 of about 73,186 (252)
A Comparative Analysis of the Murine Thymic Microenvironment in Normal, Autoimmune, and Immunodeficiency States [PDF]
, 1997 It is widely accepted that the thymic microenvironment regulates normal thymopoiesis through a highly coordinated and complex series of cellular and cytokine interactions. A direct corollary of this is that abnormalities within the microenvironment could
Ansari, Aftab A. +10 more
core +3 more sources
Ungesättigte Phosphor‐Elektrophile zur Untersuchung von Protein‐Tyrosin‐Phosphatasen
Angewandte Chemie, EarlyView.Negativ geladene Aryl‐Ethynyl‐Phosphonamid‐ und Phosphonsäuren werden als reaktionsarme Elektrophile für peptidbasierte Aktivitätssonden eingeführt, die eine selektive, zielspezifische Profilierung von Protein‐Tyrosin‐Phosphatasen ermöglichen. Die Sonden zeigen keine Off‐Target‐Cystein‐Reaktivität und binden in der globalen Proteomanalyse nur an die ...
Eleftheria Poulou +4 more
wiley +1 more source
Hydrophobic Proteome Analysis of Triple Negative and Hormone-Receptor-Positive-Her2-Negative Breast Cancer by Mass Spectrometer [PDF]
, 2010 It is widely believed that discovery of specific, sensitive, and reliable tumor biomarkers can improve the treatment of cancer. Currently, there are no obvious targets that can be used in treating triple-negative breast cancer (TNBC).
Chang, Helena R. +6 more
core +3 more sources
Unsaturated Phosphorus Electrophiles to Probe Protein Tyrosine Phosphatases
Angewandte Chemie International Edition, EarlyView.Charged aryl‐ethynyl phosphonamidic and phosphonic acids are introduced as low‐reactivity electrophiles for peptide‐based activity probes that enable selective, target‐specific profiling of protein tyrosine phosphatases. The probes show no off‐target cysteine reactivity and engage only the interacting phosphatase in global proteomic analysis.
Eleftheria Poulou +4 more
wiley +1 more source
Discovery of conserved motifs in MARCO through evolutionary analyses and molecular biology [PDF]
, 2012 Of the pattern recognition receptors involved in innate immunity, the class A Scavenger receptors are involved in the recognition and clearance of bacteria, yeast, and senescent molecules.
Whelan, Fiona J.
core
Helmeted hornbill cranial kinesis: Balancing mobility and stability in a high‐impact joint
The Anatomical Record, EarlyView.Abstract Prokinesis—in which a craniofacial joint allows the rostrum to move relative to the braincase—is thought to confer diverse advantages in birds, mostly for feeding. A craniofacial joint would, however, be a weak link if cranial stability is important. Paradoxically, we have identified a craniofacial joint in helmeted hornbills (Rhinoplax vigil),
Mike Schindler +8 more
wiley +1 more source
Effect of crude extracts from Thai herbs on growth of cultured human hair follicle: A pilot study [PDF]
, 2015 Hair loss is an anguish problem which increases in both men and women nowadays. Minoxidil and finasteride are currently used as a combined treatment of hair loss due to genetic problem.
Gerdprasert Gerdprasert, Orapin +4 more
core +1 more source
The Anatomical Record, EarlyView.An elastic segment was found in the basal part of the whisker shaft in rats and mice. Application of force to the whisker bulb of isolated follicles caused bending and twisting of this segment. Active whisker movements deform this segment, causing whisker shaft deflection and selective activation of mechanoreceptors at different phases of whisking ...
Sebastian Haidarliu +4 more
wiley +1 more source
A rare case of presacral epidermoid cyst in an adult male: emphasis on diffusion weighted magnetic resonance sequences in preoperative imaging. [PDF]
, 2018 Epidermoid cyst of the presacral space is a rare congenital lesion of ectodermal origin. Presacral epidermoid cysts have been previously reported in women, however are extremely rare in males.
Alvi, Muhammad I. +4 more
core +1 more source
The Anatomical Record, EarlyView.Abstract Hadrosaurid dinosaurs are generally regarded as “crested” or “non‐crested” depending on the presence or absence of a bony cranial crest. At least one supposedly “non‐crested” hadrosaur is known to have possessed a soft tissue cranial crest (or comb), based on an exceptionally preserved “mummified” specimen. Here we redescribe this specimen and
Henry S. Sharpe +4 more
wiley +1 more source