Results 71 to 80 of about 4,806 (208)

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

Advanced Science, Volume 13, Issue 8, 9 February 2026.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai, Tuhina Mitra, Tanmoy Pain, Jyotiprakash Mallick, Rwiddhi Chakraborty, Kallam Tejaswi, Swagata Ghatak, Sanjib Kar   +7 more
wiley   +1 more source

Ganciclovir ophthalmic gel 0.15% for the treatment of acute herpetic keratitis: background, effectiveness, tolerability, safety, and future applications

Therapeutics and Clinical Risk Management, 2014
Timothy Y Chou, Bennett Y Hong Department of Ophthalmology, Stony Brook University, Stony Brook, NY, USA Abstract: Eye disease due to herpes simplex virus (HSV) is a leading cause of ocular morbidity and the number one infectious cause of unilateral ...
Chou TY, Hong BY
doaj  

Collection of corneal impression cytology directly on a sterile glass slide for the detection of viral antigen: An inexpensive and simple technique for the diagnosis of HSV epithelial keratitis – A pilot study

BMC Ophthalmology, 2001
Background Herpes simplex keratitis (HSK) is a sight threatening ocular infection and occurs worldwide. A prompt laboratory diagnosis is often very useful. Conventional virology techniques are often expensive and time consuming. We describe here a highly
Bandlapally Sesha, Athmanathan Sreedharan, Rao Gullapalli N   +2 more
doaj   +1 more source

Confocal Microscopic Evaluation of the Inflammatory Response in Non-epithelial Herpes Simplex Keratitis

, 2012
Purpose: To investigate the characteristics of the inflammatory response detected in corneas with active non-epithelial herpes simplex virus (HSV) keratitis.
Banu Bozkurt, Anastasios G. P. Konstas, Mocan, M. C., Konstas, Anastasios G. P., Mikropoulos, Dimitrios G., Mehmet C. Mocan, Mehmet Orhan, Irkec, Murat, Murat Irkec, Irkec, M., Mikropoulos, D. G., Orhan, M., BOZKURT, BANU, MOCAN, MEHMET CEM, Bozkurt, B., Dimitrios G. Mikropoulos, Konstas, A. G. P., Orhan, Mehmet   +17 more
core   +1 more source

Applications of Multifunctional Hydrogel in Tissue Engineering and Regenerative Medicine

MedComm, Volume 7, Issue 2, February 2026.
Schematic illustration showing multifunctional hydrogels in the application of tissue engineering and regenerative medicine. ABSTRACT Hydrogels, with excellent hydrophilicity and high‐water content, have emerged as highly versatile biomaterials for tissue engineering and regenerative medicine.
Jieran Lyu, Xuemiao Liu, Qiqi Yang, Yuchang Zhang, Xing Wang   +4 more
wiley   +1 more source

Primary Herpes Simplex Subepithelial Dendritic Keratitis

American Journal of Ophthalmology, 1981
A 37-year-old man developed an acute follicular conjunctivitis with preauricular lymphadenopathy believed to be epidemic keratoconjunctivitis. On the eighth day of his disease, subepithelial dendritic opacities developed in the cornea which were not typical of either epidemic keratoconjunctivitis or herpetic keratitis.
Department of Ophthalmology, University of Florida College of Medicine, Gainesville, FloridaDepartment of OphthalmologyUniversity of Florida College of MedicineGainesvilleFlorida ( host institution ), Stern, George A., Zam, Z. Suzanne, Gutgesell, Vicki J.   +3 more
openaire   +3 more sources

Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis

Acta Ophthalmologica, Volume 104, Issue 1, Page 44-51, February 2026.
Abstract Purpose Acanthamoeba keratitis (AK) is a severe corneal infection with potential detrimental effects on visual outcome and quality of life, primarily affecting young contact lens wearers. We report Acanthamoeba genotypes, subtypes and clinical outcome from Danish patients with AK. Methods Thirty‐nine PCR‐positive AK cases diagnosed and treated
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Anders Ivarsen   +5 more
wiley   +1 more source

Expression of dectin-1 during fungus infection in human corneal epithelial cells

International Journal of Ophthalmology, 2014
AIM:To evaluate the expression of dendritic cell-associated C-type lectin-1 (dectin-1) in human corneal epithelial (HCE) cells infected by fungus.METHODS:A total of 20 cases of healthy donor corneas were group A, and 20 patients (20 eyes) suffered from ...
Cui Li, Gui-Qiu Zhao, Cheng-Ye Che, Na Li, Jing Lin, Qiang Xu, Qian Wang, Ying Liu, Sheng Qiu   +8 more
doaj   +1 more source

IL-36α Enhances Host Defense against Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas

, 2021
The IL-36 cytokines are known to play various roles in mediating the immune response to infection in a tissue- and pathogen-dependent manner. The present study seeks to investigate the role of IL-36R signaling in C57BL/6 mouse corneas in response to ...
Lee, Patrick S Y, Yu, Fu-Shin X, Me, Rao, Zhang, Yangyang, Liu, Tingting, Gao, Nan, Standiford, Theodore J, Mi, Qing-Sheng, Wang, Jie   +8 more
core  

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source