Results 61 to 70 of about 84,419 (317)

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study [PDF]

open access: yes, 2019
Background: Dry eye disease (DED) affects more than 14% of the elderly population causing decrease of quality of life, high costs and vision impairment.
Allegretti, M.   +7 more
core   +1 more source

Vision Changes After Head and Neck Cancer Treatment

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Literature about ocular toxicity after head and neck cancer (HNC) treatment is scarce. This study aimed to describe visual function and ocular symptoms among HNC patients. Methods The study used a cross‐sectional design. Two surveys, The National Eye Institute Visual Functioning Questionnaire (NEI‐VFQ) and an Ocular Symptom Scale ...
Hsiao‐Lan Wang   +7 more
wiley   +1 more source

Alternaria keratitis after corneal crosslinking

open access: yesAmerican Journal of Ophthalmology Case Reports, 2020
Purpose: To report a case of fungal keratitis after corneal collagen crosslinking (CXL) surgery. Observations: We report a case of fungal keratitis after CXL for post-refractive surgery ectasia.
Samantha McGirr   +2 more
doaj  

Epidemiological profile of fungal keratitis in urban population of West Bengal, India

open access: yesOman Journal of Ophthalmology, 2009
Background : Corneal diseases are one of the major causes of visual loss and blindness, second only to cataract. Amongst corneal diseases, microbial keratitis is a major blinding disease.
Suman Saha   +3 more
doaj   +1 more source

Ocular Surface Microbiota in Contact Lens Users and Contact-Lens-Associated Bacterial Keratitis

open access: yesVision, 2021
Our objectives were to investigate whether the conjunctival microbiota is altered by contact lens wear and/or bacterial keratitis and to explore the hypothesis that commensals of conjunctival microbiota contribute to bacterial keratitis.
Jasmine Andersson   +5 more
doaj   +1 more source

Therapeutic penetrating keratoplasty for microbial keratitis in Taiwan from 2001 to 2014

open access: yesJournal of the Formosan Medical Association, 2020
Purpose: To study the surgical outcome of therapeutic penetrating keratoplasty (TPK) for medically uncontrolled microbial keratitis at a tertiary hospital in Taiwan over a 14-year period. Methods: This is a retrospective case series study.
Teck Boon Tew   +5 more
doaj  

Phase I trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]

open access: yes, 2018
Neurotrophic keratitis/keratopathy (NK), a rare degenerative corneal disease, lacks effective pharmacologic therapies.1 Because NK pathology involves trigeminal nerve damage and loss of corneal innervation, nerve growth factor (NGF) is surmised to ...
Alio, Jorge   +45 more
core   +1 more source

Intelligent peptide‐based nanomaterials for targeted antibacterial therapy: Design, properties and applications

open access: yesResponsive Materials, EarlyView.
This review comprehensively discusses intelligent peptide‐based nanomaterials from the design, mechanisms, properties, and applications, taking stimuli responsiveness as a starting point. Abstract Bacterial infections pose a major threat to human health as well as livestock production. Traditional antibiotics face significant limitations in the complex
Chenlong Zhou   +8 more
wiley   +1 more source

A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency [PDF]

open access: yes, 2019
Producción CientíficaOcular stem cell transplantation derived from either autologous or allogeneic donor corneoscleral junction is a functional cell therapy to manage extensive and/or severe limbal stem cell deficiencies that lead to corneal epithelial ...
Alberca Zaballos, Mercedes   +9 more
core   +2 more sources

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

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