On the Keratoconjunctivitis Sicca
Keratoconjunctivitis sicca, also known as dry eye disease, is an inflammatory condition of the ocular surface caused by a pathologic reduction in the aqueous component of the tear film. Keratoconjunctivitis sicca usually manifests as dry eyes, foreign bodies, burning, itching, blurred vision, red eyes, and contact lens intolerance.
Eva Grand, Heather Mossel
openaire +4 more sources
Keratoconjunctivitis sicca (dry eye)
Keratoconjuctivitis sicca, more commonly known as dry eye, or dry eye disease, is common. It results from improper functioning of the lacrimal functional unit.
Leilani Johnston
doaj +2 more sources
Parallel mapping and simultaneous sequencing reveals deletions in BCAN and FAM83H associated with discrete inherited disorders in a domestic dog breed. [PDF]
The domestic dog (Canis familiaris) segregates more naturally-occurring diseases and phenotypic variation than any other species and has become established as an unparalled model with which to study the genetics of inherited traits. We used a genome-wide
Oliver P Forman +5 more
doaj +3 more sources
The role of inflammation and antiinflammation therapies in keratoconjunctivitis sicca
Koray Gumus1, Dwight H Cavanagh21Department of Ophthalmology, Erciyes University School of Medicine, Kayseri, Turkey; 2Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, Texas, USAPurpose: To review and integrate ...
Koray Gumus, Dwight H Cavanagh
doaj +1 more source
Differentially Expressed Tear Proteins in Sjögren's Syndrome Keratoconjunctivitis Sicca. [PDF]
Purpose: The purpose of this study was to determine if there are significant differences in the concentrations of tear proteins in Sjögren\u27s syndrome keratoconjunctivitis sicca (SS KCS) compared to healthy controls.
Yoon SP +3 more
europepmc +2 more sources
Seronegative Sicca Syndrome: Diagnostic Considerations and Management Strategies
Seronegative sicca syndrome encompasses patients who present with xerostomia and/or keratoconjunctivitis sicca but lack anti-SSA/SSB antibodies and do not fulfill current classification criteria for primary Sjögren’s syndrome (pSS).
Yordanka M. Basheva-Kraeva +11 more
doaj +2 more sources
Ocular Clinical Signs and Diagnostic Tests Most Compatible With Keratoconjunctivitis Sicca: A Latent Class Approach. [PDF]
PURPOSE: To evaluate the ocular signs and tests for keratoconjunctivitis sicca (KCS) in the absence of a gold standard. METHODS: Cross-sectional study of participants from the Sjögren's International Collaborative Clinical Alliance (SICCA) registry ...
Gonzales JA +8 more
europepmc +2 more sources
Effect of Oral Choline Alfoscerate on Patients with Keratoconjunctivitis Sicca. [PDF]
Keratoconjunctivitis sicca (KCS) or dry eye is a disease characterized by ocular surface symptoms. This study aimed to investigate the effectiveness of oral choline alfoscerate (CA) administration as a treatment for KCS.
Choi JJ, Hwang JS, Shin YJ.
europepmc +2 more sources
Autoimmunity in the pathogenesis and treatment of keratoconjunctivitis sicca. [PDF]
Dry eye is a chronic corneal disease that impacts the quality of life of many older adults. keratoconjunctivitis sicca (KCS), a form of aqueous-deficient dry eye, is frequently associated with Sjögren’s syndrome and mechanisms of autoimmunity.
Liu KC, Huynh K, Grubbs J, Davis RM.
europepmc +2 more sources
Background Sjogren’s syndrome, an autoimmune disease of the exocrine glands, results in keratoconjunctivitis sicca, xerostomia, and dental caries. It is often overlooked, considered by clinicians to be a benign disease.
Maen D. Abou Ziki +3 more
doaj +1 more source

