Results 31 to 40 of about 11,287 (243)

Signaling pathways in the regulation of cancer stem cells and associated targeted therapy

MedComm, Volume 3, Issue 4, December 2022., 2022
The major signaling pathways that regulate CSCs. Amongst an array of signaling pathways aberrantly activated in cancer Wnt, JAK/STAT, PI3k/Akt/mTOR, Notch, NF‐κB, Hedgehog, and TGF‐β/Smad pathways are crucial for the of self‐renewal, cell growth, metastasis of CSCs, and angiogenesis.
Wang Manni, Wu Min
wiley   +1 more source

Potential Biomarkers and Signaling Pathways Associated with the Pathogenesis of Primary Ameloblastoma: A Systems Biology Approach

International Journal of Dentistry, Volume 2022, Issue 1, 2022., 2022
Objective. Ameloblastoma is a benign odontogenic tumor that may lead to ameloblastic carcinoma. This study aimed to determine potential signaling pathways and biological processes, critical genes and their regulating transcription factors (TFs), and miRNAs, as well as protein kinases involved in the etiology of primary ameloblastoma. Methods.
Zeynab Bayat, Azin Mirzaeian, Amir Taherkhani, Amol Gadbail   +3 more
wiley   +1 more source

Impact of changing classification systems on prevalence and frequency distribution of odontogenic tumors in tertiary care center of Nagpur

Brazilian Journal of Otorhinolaryngology, 2022
Introduction: The classification of odontogenic tumors has been revised from time to time in order to provide unified terminology. This reclassification had considerable impact on their prevalence and frequency distribution.
Harpreet Kaur, Suchitra Gosavi, Vinay K. Hazarey, Vandana Gupta, Upendra Singh Bhadauria, Pooja Kherde   +5 more
doaj   +1 more source

Infected Dentigerous Cyst of Maxillary Sinus Mimicking Intraoral Abscess in a Pediatric Patient: Management of Misdiagnosis and Inaccurate Treatment

Case Reports in Dentistry, Volume 2022, Issue 1, 2022., 2022
The article presents the case of a 12‐year‐old male patient who was suffering from exacerbated (infected) dentigerous cyst of maxillary sinus, associated with impacted canine whose symptoms were deceptively similar to intraoral abscess. The first‐aid treatment performed by general dental practitioner consisted of intraoral incision and resulted in ...
Damian Chybicki, Alicja Popielarczyk, Wojciech Markowski, Gaja Torbicka, Anna Janas-Naze, Hamdi Cem Gungor   +5 more
wiley   +1 more source

Evaluation of urinary hydroxyproline and creatinine level in patients with benign mandibular odontogenic tumor

Clinical and Experimental Dental Research, Volume 7, Issue 5, Page 934-940, October 2021., 2021
Abstract Background Odontogenic tumors are relatively common oro‐facial tumors seen in our environment with challenges encountered with management in terms of inadequate infrastructure and high cost of treatment. They are often associated with bone resorption with concomitant collagen degradation and excretion of their by‐products in serum or urine ...
Chidozie I. Onwuka, Chibuzo C. Uguru, Chidinma I. Onwuka, Ambrose E. Obiechina   +3 more
wiley   +1 more source

Transcriptome Variability in Keratocystic Odontogenic Tumor Suggests Distinct Molecular Subtypes. [PDF]

Sci Rep, 2016
Keratocystic Odontogenic Tumor (KCOT) is a locally aggressive developmental cystic neoplasm thought to arise from the odontogenic epithelium. A high recurrence rate of up to 30% has been found following conservative treatment.
Hu S, Divaris K, Parker J, Padilla R, Murrah V, Wright JT.   +5 more
europepmc   +2 more sources

Cyclooxygenase‐2 protein expression modulates cell proliferation and apoptosis in solid ameloblastoma and odontogenic keratocyst. An immunohistochemical study

Journal of Oral Pathology &Medicine, Volume 50, Issue 9, Page 937-945, October 2021., 2021
Abstract Background Cyclooxygenase‐2 protein is a critically important mediator in inflammation that influences proliferation, apoptosis, angiogenesis and metastasis. Previous works showed a relationship between cyclooxygenase‐2 and tumourigenesis in humans and animal models. In epithelial odontogenic tumours and cysts, increased cell proliferation and
Enrico Escobar, Cristian Peñafiel, Fernán Gómez‐Valenzuela, Eduardo Chimenos‐Küstner, Ricardo Pérez‐Tomás   +4 more
wiley   +1 more source

Immunohistochemical expression of protein 53, murine double minute 2, B-cell lymphoma 2, and proliferating cell nuclear antigen in odontogenic cysts and keratocystic odontogenic tumor

Indian Journal of Dental Research, 2013
Introduction: Even though odontogenic cysts share a similar histogenesis, they show different growth and differentiation profile due to differences in the proliferative cellular activity. Aims: We perform an immunohistochemical assessment of protein 53 (
Hébel Cavalcanti Galvão, Manuel Antonio Gordón-Núñez, Rivadávio Fernandes Batista de Amorim, Roseana de Almeida Freitas, Lélia Batista de Souza   +4 more
doaj   +1 more source

Microdeletion of 9q22.3: A patient with minimal deletion size associated with a severe phenotype

American Journal of Medical Genetics Part A, Volume 185, Issue 7, Page 2070-2083, July 2021., 2021
Abstract Basal cell nevus syndrome (also known as Gorlin Syndrome; MIM109400) is an autosomal dominant disorder characterized by recurrent pathological features such as basal cell carcinomas and odontogenic keratocysts as well as skeletal abnormalities.
Adam D. Ewing, Seth W. Cheetham, James J. McGill, Michael Sharkey, Rick Walker, Jennifer A. West, Malcolm J. West, Kim M. Summers   +7 more
wiley   +1 more source

A Comparative Immunohistochemical Expression of Cyclin D1 in Keratocystic Odontogenic Tumor, Dentigerous and Radicular Cysts

Journal of Baghdad College of Dentistry, 2016
Background: Odontogenic cysts include a group of osseodestructive lesions that frequently affect the jaws. Those cysts could derive from odontogenic epithelium and occur in the tooth-bearing regions of the jaws.
Yasamin H Al-Amiri, Lehadh M Al-Azzawi   +1 more
doaj   +1 more source