Results 21 to 30 of about 1,636 (159)
The Multifaceted Role of Keratinocytes in Hidradenitis Suppurativa Pathogenesis. [PDF]
ABSTRACT Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin disorder of the pilosebaceous unit, with multiple factors contributing to its onset, activity and progression. Alongside a predisposing genetic background, hormonal and microbiome alterations, dysregulation of innate and adaptive immune response, as well as environmental ...
Moltrasio C, Marzano AV, Romagnuolo M.
europepmc +2 more sources
The use of urea for skin barrier correction [PDF]
The review summarizes information about the main causes and pathogenesis of xerosis cutis as one of the conditions indicating a violation of the epidermal barrier.
Vera I. Albanova +2 more
doaj +1 more source
Testing keratolytic effect of carbamide in various vehicles [PDF]
Background. Urea is a natural protein degradation product widely used in keratolytic preparations due to its property to promote fibrinogen decomposition and to act as a proteolytic agent dissolving and denaturing proteins. Preparations containing 20% or
Toskić-Radojičić Marija
doaj +1 more source
Successful use of dupilumab for treatment-resistant pityriasis amiantacea
Pityriasis amiantacea (PA) is a scalp condition characterized by thick, adherent scales that are silvery or yellow–gray in color and bind down tufts of hair. PA is associated with several underlying dermatologic conditions including psoriasis, seborrheic
Maya Firsowicz +3 more
doaj +1 more source
Terra firma-forme dermatosis: a condition not to be forgotten (a case report)
Introduction: Terra firma-forme dermatosis is a benign condition and it can affect anyone, but it seems to be more common in children and young adults. It may appear as brownish or black spots that look like dirt.
Irina Cristóvão +4 more
doaj +1 more source
Pityriasis versicolor is a common fungal infection of the superficial skin layer caused by Malassezia furfur, a normal commensal in the skin. Keratolytic agents are popular, cheap, and readily available over-the-counter treatments for pityriasis versicolor.
Genuino, Rowena Natividad F. +4 more
openaire +2 more sources
Mal de Meleda : a case successfully treated with acitretin
Mal de Meleda (MdM) is an autosomal recessive form of palmoplantar keratoderma, that is characterized by transgradient keratoderma with associated scleroatrophy, nail changes, pseudoainhum around digits and perioral erythema, without a tendency for ...
Kaoutar Achehboune +3 more
doaj +1 more source
Darier's follicular dyskeratosis
Darier's follicular dyskeratosis (synonym: Dariers disease, DarierWhites disease) is a rare genetic disease with an autosomal dominant type of inheritance, which belongs to the group of acantholytic dermatoses and is characterized by a violation of ...
Uladzimir P. Adaskevich
doaj +1 more source
Placebo-Controlled Trial to Determine the Effectiveness of a Urea/Lactic Acid–Based Topical Keratolytic Agent for Prevention of Capecitabine-Induced Hand-Foot Syndrome: North Central Cancer Treatment Group Study N05C5 [PDF]
Purpose Hand-foot syndrome (HFS) is a dose-limiting toxicity of capecitabine for which no effective preventative treatment has been definitively demonstrated. This trial was conducted on the basis of preliminary data that a urea/lactic acid–based topical keratolytic agent (ULABTKA) may prevent HFS.
Sherry L, Wolf +10 more
openaire +2 more sources
Warts of the Nail Unit: Surgical and Nonsurgical Approaches
Background. Warts are the most common nail tumor and mostly affect children and young adults. Periungual warts are usually due to HPV‐1, 2, and 4. Development of periungual warts is favored by maceration and trauma, especially nail biting. Objective.
Piraccini, Bianca Maria +1 more
core +2 more sources

