Real-World Treatment Patterns and Healthcare Costs in Patients with Psoriatic Arthritis Treated with Ixekizumab: A Retrospective Study. [PDF]
Objective To describe adherence, persistence, discontinuation, restarting, switching, dosing, and health care costs among patients with psoriatic arthritis (PsA) treated with ixekizumab (IXE). Methods MarketScan administrative claims databases were used to select adults (≥18 years) initiating IXE between January 1, 2016, and June 30, 2019, for this ...
Murage MJ +9 more
europepmc +2 more sources
Carbon content, carbon fixation yield and dissolved organic carbon release from diverse marine nitrifiers. [PDF]
Abstract Nitrifying microorganisms, including ammonia‐oxidizing archaea, ammonia‐oxidizing bacteria, and nitrite‐oxidizing bacteria, are the most abundant chemoautotrophs in the ocean and play an important role in the global carbon cycle by fixing dissolved inorganic carbon (DIC) into biomass.
Bayer B +3 more
europepmc +2 more sources
A UK-wide survey evaluation of capnography variation. [PDF]
Anaesthesia, Volume 80, Issue 6, Page 716-719, June 2025.
Shepherd AA +5 more
europepmc +2 more sources
Maternal Use of Physical Discipline and Children's Externalizing Problems Across Childhood in Singapore. [PDF]
ABSTRACT This study explored the reciprocal associations between maternal physical discipline and children's externalizing problems across childhood, distinguishing between trait‐like (i.e., between‐person) and state‐like (i.e., within‐person) differences.
Kyeong Y +9 more
europepmc +2 more sources
Patient-reported outcomes, postoperative pain and pain relief after day-case surgery (POPPY): chronic post-surgical pain prevalence and associations. [PDF]
Summary Introduction Day‐case surgical activity is increasing in the UK yet there is a lack of data on the prevalence of chronic post‐surgical pain in this population. This study uses data from the POPPY study to estimate the prevalence of chronic post‐surgical pain after day‐case surgery, its relationship with quality of life and also explores ...
Brayne AB +9 more
europepmc +2 more sources
Effects of human demand on conservation planning for biodiversity and ecosystem services. [PDF]
Abstract Safeguarding ecosystem services and biodiversity is critical to achieving sustainable development. To date, ecosystem services quantification has focused on the biophysical supply of services with less emphasis on human beneficiaries (i.e., demand).
Watson KB +4 more
europepmc +2 more sources
Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons. [PDF]
Abstract Brain‐derived neurotrophic factor (Bdnf) plays a critical role in brain development, dendritic growth, synaptic plasticity, as well as learning and memory. The rodent Bdnf gene contains nine 5′ non‐coding exons (I–IXa), which are spliced to a common 3′ coding exon (IX).
Bach SV +9 more
europepmc +2 more sources
Experiences of healthcare providers and caregivers regarding health system bottlenecks affecting child healthcare service delivery in a rural district: Empirical qualitative study. [PDF]
Abstract Aim To explore the experiences of nurses and caregivers about the health system bottlenecks to the delivery of child healthcare services in a rural district in Ghana. Design The study employed a qualitative approach using an exploratory, descriptive design. Methods Collection of data was through semi‐structured, face‐to‐face interviews with 26
Nyande FK +3 more
europepmc +2 more sources
Beyond Personalization: Embracing Democratic Learning Within Artificially Intelligent Systems
Abstract This essay explains how, from the theoretical perspective of Basil Bernstein's three “conditions for democracy,” the current pedagogy of artificially intelligent personalized learning seems inadequate. Building on Bernstein's comprehensive work and more recent research concerned with personalized education, Natalia Kucirkova and Sandra Leaton ...
Natalia Kucirkova, Sandra Leaton Gray
wiley +1 more source
Victor McKusick and his short course
Abstract The Short Course in Human and Mammalian Genetics and Genomics (aka the “Short Course” or the “Bar Harbor course”) is one of Victor McKusick's landmark contributions to medical genetics. Conceived in 1959 as a way to increase the contribution of genetic advances to medicine, it has directly affected more than 7000 students and 600 participating
Charles Wray, Gregory Cox, David Valle
wiley +1 more source

