Results 221 to 230 of about 120,097 (295)

Scalable geometric learning with correlation-based functional brain networks. [PDF]

Sci Rep
You K, Lee Y, Park HJ.
europepmc   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

Advanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou, Mingkun Lu, Zhimeng Zhou, Yanlin Ren, Xinyuan Yu, Ziqi Pan, Yuan Zhou, Hao Yang, Lingyan Zheng, Shukai Gu, Yang Zhang, Wei Hu, Fengcheng Li, Haibin Dai, Feng Zhu   +14 more
wiley   +1 more source

Kernel generalized least squares regression for network-structured data. [PDF]

PLoS One
Antonian E, Peters GW, Chantler M.
europepmc   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Machine learning-based survival prediction in colorectal cancer combining clinical and biological features. [PDF]

Oncotarget
Vieira LM, Jorge NAN, Sousa JB, Setubal JC, Stadler PF, Walter MEMT.   +5 more
europepmc   +1 more source

A Wireless, Battery‐Free Artificial Throat Patch with Deep Learning for Emotional Speech Recognition

Advanced Science, EarlyView.
In this work, Xu and co‐workers develop a wireless, battery‐free artificial throat patch system (ATPS) consisting of a carbon nanotube‐based thin‐film strain sensor and a miniaturized flexible printed circuit board, to enable real‐time sensing of throat signals.
Bingxin Xu, Guanming Lin, Xiaohui Hong, Chuting Liu, Xinyi Qu, Kangjian Jiao, Lei Zhang, Bingzhe Xu, Jun Yan, Yancong Qiao, Xudong Lin   +10 more
wiley   +1 more source

Efficient Testing Using Surrogate Information. [PDF]

Biom J
Knowlton R, Parast L.
europepmc   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

tvsfglasso: Time-varying scale-free graphical lasso for network estimation from time-series data. [PDF]

PLoS Comput Biol
Kuismin M, Sillanpää MJ.
europepmc   +1 more source