CellPolaris decodes how transcription factors guide cell fate by building gene regulatory networks from transcriptomic data using transfer learning. It generates tissue‐ and cell‐type‐specific networks, identifies master regulators in cell state transitions, and simulates TF perturbations in developmental processes.
Guihai Feng +27 more
wiley +1 more source
Corrigendum to "Phase-lag mixed integral equation of a generalized symmetric potential kernel and its physical meanings in (3+1) dimensions" [Heliyon Volume 11, Issue 3, February 2025, Article e42316]. [PDF]
Jan AR.
europepmc +1 more source
Forward-backward kernel-based state and parameter estimation for linear systems of arbitrary order [PDF]
Debarshi Patanjali Ghoshal, H. Michalska
openalex +1 more source
Immune Predictors of Radiotherapy Outcomes in Cervical Cancer
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang +8 more
wiley +1 more source
Generalized M-Estimation-Based Framework for Robust Guidance Information Extraction. [PDF]
Ren J, Zhang X, Li S, Tan P.
europepmc +1 more source
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng +20 more
wiley +1 more source
Regression approaches for modeling genotype-environment interaction and making predictions into unseen environments. [PDF]
Hrachov M +3 more
europepmc +1 more source
Dipole-dipole scattering: summing large Pomeron loops in non-linear evolution with leading twist kernel [PDF]
Eugene Levin
openalex
An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar +6 more
wiley +1 more source

