Advanced Science, EarlyView.SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source
Enhanced Stability in Zero‐Excess Li‐Metal Batteries via Prelithiated Carbon Nanofiber Interlayers
Advanced Science, EarlyView.Carbon nanofibers carbonized at 700°C show Li metal deposition predominantly on the side facing the Cu current collector. During delithiation, Li agglomerates remain as inactive lithium on the fiber surface. This behavior can be changed by a modified n‐Buli prelithiation without a washing step, suppressing dead Li formation and therefore enabling ...
Sandro Schöner +11 more
wiley +1 more source
Letters of a given size in Catalan words [PDF]
Discrete Mathematics LettersAubrey Blecher, Arnold Knopfmacher
doaj +1 more source
DLoG - automatic disc based laplacian of gaussian operator for carotid artery boundary extraction in ultrasound images. [PDF]
Sci RepAnitha M, Gupta AK, Pai P, V C R.
europepmc +1 more source
Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation
Advanced Science, EarlyView.Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang +6 more
wiley +1 more source
A Genetic Algorithm-Optimized Kernel Density Estimation and D-S Evidence Fusion Classification for Predicting the Stability of Double Perovskite Materials. [PDF]
Materials (Basel)Liang G, Zhang J.
europepmc +1 more source
A Data‐Driven Inverse Design Methodology for Magnetic Soft Millirobots Navigating in Confined Spaces
Advanced Science, EarlyView.A data‐efficient inverse design framework automates the optimization of magnetic soft millirobots for confined‐space navigation. Integrating a physics‐based Cosserat rod model with Bayesian optimization efficiently identifies high‐performance geometries.
Ziyu Ren +5 more
wiley +1 more source
RF-SVR-based prediction methodology for metal tube-bending rebound: Handling non-uniformity and limited sample challenges. [PDF]
PLoS OneFang Z, Zhang P, Li L, Zhang Q.
europepmc +1 more source
Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity
Advanced Science, EarlyView.This work introduces a compact, low‐cost tabletop magnetic resonance elastography platform for high‐resolution viscoelastic mapping in soft‐tissue specimens. Using this method in human colorectal liver metastases, we demonstrate fully automated biomechanical profiling of treatment response and show that heterogeneity‐based metrics outperform ...
Weijie Zhao +19 more
wiley +1 more source
Integrating Distance Correlation and Adaptive Weighting with RBF Kernel Transformations: A Novel Feature Selection Framework with Application to ECG Arrhythmia Detection. [PDF]
Bioengineering (Basel)Fira M, Fira L.
europepmc +1 more source