Results 161 to 170 of about 114,264 (263)

Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin   +9 more
wiley   +1 more source

Bradykinin/bradykinin 1 receptor promotes brain microvascular endothelial cell permeability and proinflammatory cytokine release by downregulating Wnt3a

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 36, Issue 12, December 2022., 2022
Abstract Stroke is a life‐threatening disease with limited therapeutic options. Damage to the blood–brain barrier (BBB) is the key pathological feature of ischemic stroke. This study explored the role of the bradykinin (BK)/bradykinin 1 receptor (B1R) and its mechanism of action in the BBB.
Linqiang Huang   +8 more
wiley   +1 more source

Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in male and female Sprague-Dawley rats

open access: yesIBRO Neuroscience Reports, 2021
Although ketamine, a multimodal dissociative anesthetic, is frequently used for analgesia and treatment-resistant major depression, molecular mechanisms of ketamine remain unclear.
Michael Zhang   +4 more
doaj  

Viral metagenomic analysis reveals potential biological hazards in non‐human primates in a zoo

open access: yesAnimal Research and One Health, EarlyView.
The investigation identifies the presence of Encephalomyocarditis virus (EMCV), Baboon endogenous virus (BAV), Human endogenous retrovirus (HERV), and Baboon endogenous virus (BaEV) in non‐human primates (NHPs) at the Zoo, indicating potential zoonotic threats.
Ruiying Liang   +13 more
wiley   +1 more source

Involvement of Serotonin Receptor Mechanisms in the Discriminative Stimulus Effects of Ketamine in Rats

open access: yesJournal of Pharmacological Sciences, 2013
We have demonstrated previously that the ketamine-induced discriminative stimulus effect is likely to reflect the phencyclidine-like psychotomimetic effects. Therefore, the present study was designed to investigate the effects of the antipsychotics and 5-
Kazumi Yoshizawa   +7 more
doaj  

Ketamine for Delivery [PDF]

open access: bronze, 1976
S. GALLOON
openalex   +1 more source

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