Results 171 to 180 of about 290,727 (340)

Computer Simulation of Sulfated Cyclodextrin–Based Enantioselective Separation of Weak Bases With Partial, High‐Concentration Filling of the Chiral Selector and Analyte Detection on the Cathodic Side

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Computer simulation was utilized to characterize the electrophoretic processes occurring during the enantioselective capillary electrophoresis–mass spectrometry (CE–MS) analysis of ketamine, norketamine, and hydroxynorketamine in a system with partial filling of the capillary with 19 mM (equals 5%) of highly sulfated γ‐cyclodextrin (HS‐γ‐CD ...
Friederike A. Sandbaumhüter   +1 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Ketamine and the laryngeal reflex. [PDF]

open access: bronze, 1972
Michaël Sage, S. M. Laird
openalex   +1 more source

An algorithm for seizure detection in rodents

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky   +9 more
wiley   +1 more source

Effect of Ketamine-Sufentanil and Ketamine-Midazolam to Induce Sedation and Analgesia in Pediatric with Lumbar Puncture or Bone Marrow Aspiration

open access: yesArchives of Anesthesia and Critical Care, 2018
Background: The combination of sedative and analgesic drugs has a favorable effect on pain management and sedation during painful procedures in pediatrics.
Hamidreza Shetabi   +2 more
doaj  

Circulatory Responses to Ketamine Anesthesia [PDF]

open access: bronze, 1972
W. A. Tweed, M. Minuck, David Mymin
openalex   +1 more source

The Efficacy of Pharmacological Treatment of Depression in Anorexia Nervosa and Underweight Patients: A Systematic Review

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Major depressive disorder (MDD) is a frequent comorbidity in anorexia nervosa (AN). This review aimed to evaluate evidence on the effectiveness of pharmacological treatments for MDD in underweight individuals. Method A systematic review was conducted using PubMed, Medline, PsycINFO, and Web of Science through March 2025.
M. J. Besjes   +3 more
wiley   +1 more source

Distribution in the Brain and Metabolism of Ketamine in the Rat after Intravenous Administration [PDF]

open access: bronze, 1973
Marlene L. Cohen   +3 more
openalex   +1 more source

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