Results 171 to 180 of about 290,727 (340)
ABSTRACT Computer simulation was utilized to characterize the electrophoretic processes occurring during the enantioselective capillary electrophoresis–mass spectrometry (CE–MS) analysis of ketamine, norketamine, and hydroxynorketamine in a system with partial filling of the capillary with 19 mM (equals 5%) of highly sulfated γ‐cyclodextrin (HS‐γ‐CD ...
Friederike A. Sandbaumhüter+1 more
wiley +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang+3 more
wiley +1 more source
An algorithm for seizure detection in rodents
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky+9 more
wiley +1 more source
Background: The combination of sedative and analgesic drugs has a favorable effect on pain management and sedation during painful procedures in pediatrics.
Hamidreza Shetabi+2 more
doaj
Circulatory Responses to Ketamine Anesthesia [PDF]
W. A. Tweed, M. Minuck, David Mymin
openalex +1 more source
ABSTRACT Objective Major depressive disorder (MDD) is a frequent comorbidity in anorexia nervosa (AN). This review aimed to evaluate evidence on the effectiveness of pharmacological treatments for MDD in underweight individuals. Method A systematic review was conducted using PubMed, Medline, PsycINFO, and Web of Science through March 2025.
M. J. Besjes+3 more
wiley +1 more source
Distribution in the Brain and Metabolism of Ketamine in the Rat after Intravenous Administration [PDF]
Marlene L. Cohen+3 more
openalex +1 more source