De Novo Generation-Based Design of Potential Computational Hits Targeting the GluN1-GluN2A Receptor. [PDF]
Liu Y +6 more
europepmc +1 more source
Abstract Background and aims Recreational ketamine use has increased globally and is associated with psychiatric and cognitive concerns. The hippocampus in preclinical models shows damage and working‐memory disruption with repeated dosing. However, whether specific hippocampal subregions may differ in people with chronic ketamine use remains unclear ...
Yi‐Hsuan Liu +8 more
wiley +1 more source
Time matters for metas: a systematic review and meta-analysis of ect vs ketamine for depression incorporating time. [PDF]
Nikolin S +3 more
europepmc +1 more source
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley +1 more source
Ketamine for Severe Asthma Exacerbation. [PDF]
Wagner EM +4 more
europepmc +1 more source
Changes over time in hallucinogen‐related emergency department visits in Ontario, Canada
Abstract Background and aims Recent increasing interest in hallucinogens has underscored the critical gaps in our understanding of their adverse health effects and healthcare usage over time. The current study aimed to examine changes in emergency department (ED) visit rates involving hallucinogens, clinical outcomes of visits and the characteristics ...
Daniel T. Myran +9 more
wiley +1 more source
Evaluation of Current Evidence on the Efficacy of Esketamine in Treating Substance-Use Disorders in Patients With Treatment-Resistant Depression (TRD): A Narrative Review. [PDF]
Shelke S, Thummalapally RR.
europepmc +1 more source
Brief report: Ketamine‐assisted “bridge therapy” for opioid tapering in complex cases
Abstract Background Opioid use disorder (OUD) presents major challenges, especially when combined with chronic pain and psychiatric comorbidities. A 25‐year‐old woman with OUD, chronic pain, and major depressive disorder underwent an 8‐week protocol of intravenous ketamine infusions (0.5 mg/kg weekly) as an adjunct to opioid tapering. Results Methadone
Mariana C. de Oliveira +11 more
wiley +1 more source
Potential molecular pathways and therapeutic implications of rapid-acting antidepressants on myelin biology: a scoping review. [PDF]
Inserra A +4 more
europepmc +1 more source
RETRACTION: Effect of Combined Etomidate-Ketamine Anesthesia on Perioperative Electrocardiogram and Postoperative Cognitive Dysfunction of Elderly Patients with Rheumatic Heart Valve Disease Undergoing Heart Valve Replacement. [PDF]
Healthcare Engineering JO.
europepmc +1 more source

