Results 301 to 310 of about 225,419 (363)

Excess Fructose Intake Activates Hyperinsulinemia and Mitogenic MAPK Pathways in Association With Cellular Stress, Inflammation, and Apoptosis in the Pancreas of Rats

Molecular Nutrition &Food Research, EarlyView.
This study highlights the possible mechanisms underlying the detrimental effects of high‐fructose consumption on pancreatic function. Our findings revealed that dietary high‐fructose in the pancreas causes hyperinsulinemia due to the upregulation of glucose transporter 2 (GLUT2) together with cellular stress and inflammatory markers, thereby stimulates
Ceren Guney, Mehmet Eray Alcigir, Fatma Akar   +2 more
wiley   +1 more source

Prediction of individual treatment allocation between electroconvulsive therapy or ketamine using the Personalized Advantage Index. [PDF]

NPJ Digit Med
Wade BSC, Pindale R, Luccarelli J, Li S, Meisner RC, Seiner SJ, Camprodon JA, Henry ME.   +7 more
europepmc   +1 more source

Protective Effects of Propolis Supplementation on Aflatoxin B1‐Induced Oxidative Stress, Antioxidant Status, Intestinal Barrier Damage, and Gut Microbiota in Rats

Molecular Nutrition &Food Research, EarlyView.
In rats exposed to aflatoxin B1 (AFB1), propolis supplementation may alleviate oxidative stress by exhibiting antioxidant effects and restore intestinal permeability impaired by AFB1 by ameliorating intestinal barrier damage. Furthermore, propolis supplementation may contribute to the modulation of the gut microbiota by preventing a decrease in the ...
Sevtap Kabalı, Mehtap Ünlü Söğüt, Neslihan Öner, Ayça Kara   +3 more
wiley   +1 more source

Leucine Supplementation Counteracts the Atrophic Effects of HDAC4 in Rat Skeletal Muscle Submitted to Hindlimb Immobilization

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims We previously demonstrated that leucine supplementation significantly reduces histone deacetylase 4 (HDAC4) expression induced by hindlimb immobilization, thereby attenuating the increase in HDAC4 protein levels and nuclear accumulation.
Paula K. N. Alves, André Cruz, William J. Silva, Afonso M. Melazzo, Siegfried Labeit, Volker Adams, Anselmo S. Moriscot   +6 more
wiley   +1 more source

Age‐Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice

Pediatric Discovery, EarlyView.
This study examined the relationship between aortic arch stiffness and lung function in aging mice. Multiple linear regression modeling showed moderate to strong correlations between the rise in aortic arch stiffness and changes in lung function as the mice progressively aged.
Ayman Isbatan, Samuel M. Lee, Ali Imran Sarwar, Yuxing Yuan, Sunny Chen, Maricela Castellon, Dan A. Marian, Richard D. Minshall, Jie Tian, Irena Levitan, Jiwang Chen   +10 more
wiley   +1 more source

HDL Nanodiscs Loaded with Liver X Receptor Agonist Decreases Tumor Burden and Mediates Long‐term Survival in Mouse Glioma Model

Small, EarlyView.
Synthetic high‐density lipoprotein (sHDL) nanodiscs are developed to co‐deliver liver‐X‐Receptor (LXR) agonists and Toll‐like receptor 9 (TLR‐9) agonist CpG for glioma treatment. By upregulation of ATP‐binding cassette transporter A1 (ABCA1), LXR agonists synergize with sHDL nanodiscs to deplete cholesterol and induce apoptosis of glioma cells.
Troy A. Halseth, Anzar A. Mujeeb, Lisha Liu, Kaushik Banerjee, Nigel Lang, Todd Hollon, Minzhi Yu, Mark Vander Roest, Ling Mei, Hongliang He, Maya Sheth, Maria G. Castro, Anna Schwendeman   +12 more
wiley   +1 more source

Clinical trials since 2020 of rapid anti-suicidal ideation effects of ketamine and its enantiomers: a systematic review. [PDF]

Transl Psychiatry
Sajid S, Mann JJ, Grunebaum MF.
europepmc   +1 more source

BLOOD VISCOSITY DURING ANAESTHESIA WITH HALOTHANE, CYCLOPROPANE, THIOPENTONE AND KETAMINE

, 1974
F Magora, M London, D Eimerl, H. B. Aronson   +3 more
openalex   +1 more source

Functional Microendoscopy Reveals Calcium Responses of Single Cells in Tracheal Tuft Cells and Kidney Podocytes

Small, EarlyView.
A cost‐effective multicore‐fiber microendoscope for biological functional imaging is presented. The instrument is thin enough to image within the mouse trachea. It is applied to record responses of tracheal tuft cells to stimulation in vivo, as well as calcium and redox signals from various organs in situ.
Tobias A. Dancker, Mohamed Ibrahem Elhawy, Ramona Rittershauß, Qinghai Tian, Yvonne Schwarz, Markus D. A. Hoffmann, Christopher Carlein, Amanda Wyatt, Vanessa Wahl, Daniel Speyerer, Alaa Kandah, Ulrich Boehm, Leticia Prates Roma, Dieter Bruns, Peter Lipp, Gabriela Krasteva‐Christ, Marcel A. Lauterbach   +16 more
wiley   +1 more source

Sleep-administered ketamine/psychedelics: A streamlined strategy to address two challenges in research on ketamine and psychedelics. [PDF]

Eur Psychiatry
Arjmand S, Lindström MB, Sellgren CM, Wegener G.   +3 more
europepmc   +1 more source