Results 311 to 320 of about 235,967 (343)
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The semantics of ketamine

Annals of Emergency Medicine, 2000
Abstract [Green SM, Krauss B. The semantics of ketamine. Ann Emerg Med. November 2000;36:480-482.]
Steven M. Green, Baruch Krauss
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Ketamine

Anaesthesia, 2007
SummaryKetamine is a very versatile inexpensive drug and plays an invaluable role in the developing world. In regions where access and funding for a wider range of drugs is problematic, its broad range of clinical applications is ideal. Its good safety profile and ease of storage makes it ideal for use in areas where refrigerators, complex monitoring ...
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Relative potency of ketamine and S(+)‐ketamine in dogs

Journal of Veterinary Pharmacology and Therapeutics, 2008
The aim of this study was to determine the relative potency of racemic ketamine and S(+)‐ketamine for the hypnotic effect and to evaluate the clinical anesthesia produced by equianesthetic doses of these two substances in dogs. One hundred and eight dogs were allocated in groups R2, R2.5, R3, R6, R9, R12, S2, S2.5, S3, S6, S9, and S12, to receive by ...
Duque, J. C.   +4 more
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Ketamine

2008
There are two optical isomers of the 2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone ketamine: S(+) ketamine and R(-) ketamine. Effects of this drug are mediated by N-methyl-d-aspartate (NMDA), opioid, muscarinic and different voltage-gated receptors.
B, Sinner, B M, Graf
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Stereoselective pharmacokinetics of ketamine: R(–)-Ketamine inhibits the elimination of S(+)-ketamine

Clinical Pharmacology & Therapeutics, 2001
ObjectiveWe investigated the pharmacokinetics of ketamine with special regard to enantiomer‐specific differences.MethodsTen healthy young male volunteers (mean age, 28 ± 4 years; mean weight, 79 ± 11 kg) received racemic ketamine and S(+)‐ketamine in a randomized double‐blind crossover study. Drugs were administered by a computer‐controlled device. Two
Gerd Geisslinger   +5 more
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The use of ketamine or ketamine–midazolam for adenotonsillectomy

International Journal of Pediatric Otorhinolaryngology, 2007
Ketamine's role in clinical anaesthesia is developing as a result of the evolving concepts of its mechanism of action and the advantages of its alternative routes of administration. In this study, we aimed to investigate the frequency and severity of adverse effects, specifically emergence phenomena and vomiting, when ketamine with or without midazolam
Nezihe Ferah Donmez   +3 more
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Why ketamine

Epilepsy & Behavior, 2023
We present the rationale for testing ketamine as an add-on therapy for treating benzodiazepine refractory (established) status epilepticus. In animal studies, ketamine terminates benzodiazepine refractory status epilepticus by interfering with the pathophysiological mechanisms and is a neuroprotectant.
Lisa, Coles   +9 more
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Ketamine

2013
Ketamine was introduced as an anaesthetic in the 1960s and continues to be used therapeutically both as an anaesthetic and also increasingly in pain management. In addition to use in humans, ketamine is widely used as an anaesthetic in veterinary medicine. It is used in research as a pharmacological model of schizophrenia. In recent years, ketamine has
Yew, DT   +8 more
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Ketamine in neuropsychiatric disorders: an update

Neuropsychopharmacology, 2023
J. Johnston   +4 more
semanticscholar   +1 more source

KETAMINE

The Lancet, 1970
J A, Gorringe   +3 more
openaire   +5 more sources

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