Results 331 to 340 of about 225,419 (363)
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American Journal of Psychiatry, 2021
OBJECTIVE Adolescent depression is prevalent and is associated with significant morbidity and mortality. Although intravenous ketamine has shown efficacy in adult treatment-resistant depression, its efficacy in pediatric populations is unknown.
J. Dwyer +8 more
semanticscholar +1 more source
OBJECTIVE Adolescent depression is prevalent and is associated with significant morbidity and mortality. Although intravenous ketamine has shown efficacy in adult treatment-resistant depression, its efficacy in pediatric populations is unknown.
J. Dwyer +8 more
semanticscholar +1 more source
Veterinary Record, 2016
FURTHER to our recent letter in Veterinary Record (March 12, 2016, vol 178, p 271), we would like to give an update on the international scheduling of ketamine following the 59th meeting of the UN Commission on Narcotic Drugs which took place in Vienna from March 14 to 22. Ketamine was discussed at some length during …
Walt Ingwersen, Polly M Taylor
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FURTHER to our recent letter in Veterinary Record (March 12, 2016, vol 178, p 271), we would like to give an update on the international scheduling of ketamine following the 59th meeting of the UN Commission on Narcotic Drugs which took place in Vienna from March 14 to 22. Ketamine was discussed at some length during …
Walt Ingwersen, Polly M Taylor
openaire +4 more sources
Annals of Emergency Medicine, 2000
Abstract [Green SM, Krauss B. The semantics of ketamine. Ann Emerg Med. November 2000;36:480-482.]
Steven M. Green, Baruch Krauss
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Abstract [Green SM, Krauss B. The semantics of ketamine. Ann Emerg Med. November 2000;36:480-482.]
Steven M. Green, Baruch Krauss
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Anaesthesia, 2007
SummaryKetamine is a very versatile inexpensive drug and plays an invaluable role in the developing world. In regions where access and funding for a wider range of drugs is problematic, its broad range of clinical applications is ideal. Its good safety profile and ease of storage makes it ideal for use in areas where refrigerators, complex monitoring ...
openaire +3 more sources
SummaryKetamine is a very versatile inexpensive drug and plays an invaluable role in the developing world. In regions where access and funding for a wider range of drugs is problematic, its broad range of clinical applications is ideal. Its good safety profile and ease of storage makes it ideal for use in areas where refrigerators, complex monitoring ...
openaire +3 more sources
Relative potency of ketamine and S(+)‐ketamine in dogs
Journal of Veterinary Pharmacology and Therapeutics, 2008The aim of this study was to determine the relative potency of racemic ketamine and S(+)‐ketamine for the hypnotic effect and to evaluate the clinical anesthesia produced by equianesthetic doses of these two substances in dogs. One hundred and eight dogs were allocated in groups R2, R2.5, R3, R6, R9, R12, S2, S2.5, S3, S6, S9, and S12, to receive by ...
Duque, J. C. +4 more
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2008
There are two optical isomers of the 2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone ketamine: S(+) ketamine and R(-) ketamine. Effects of this drug are mediated by N-methyl-d-aspartate (NMDA), opioid, muscarinic and different voltage-gated receptors.
B, Sinner, B M, Graf
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There are two optical isomers of the 2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone ketamine: S(+) ketamine and R(-) ketamine. Effects of this drug are mediated by N-methyl-d-aspartate (NMDA), opioid, muscarinic and different voltage-gated receptors.
B, Sinner, B M, Graf
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Clinical Pharmacology & Therapeutics, 2001
ObjectiveWe investigated the pharmacokinetics of ketamine with special regard to enantiomer‐specific differences.MethodsTen healthy young male volunteers (mean age, 28 ± 4 years; mean weight, 79 ± 11 kg) received racemic ketamine and S(+)‐ketamine in a randomized double‐blind crossover study. Drugs were administered by a computer‐controlled device. Two
Gerd Geisslinger +5 more
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ObjectiveWe investigated the pharmacokinetics of ketamine with special regard to enantiomer‐specific differences.MethodsTen healthy young male volunteers (mean age, 28 ± 4 years; mean weight, 79 ± 11 kg) received racemic ketamine and S(+)‐ketamine in a randomized double‐blind crossover study. Drugs were administered by a computer‐controlled device. Two
Gerd Geisslinger +5 more
openaire +3 more sources
Epilepsy & Behavior, 2023
We present the rationale for testing ketamine as an add-on therapy for treating benzodiazepine refractory (established) status epilepticus. In animal studies, ketamine terminates benzodiazepine refractory status epilepticus by interfering with the pathophysiological mechanisms and is a neuroprotectant.
Lisa, Coles +9 more
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We present the rationale for testing ketamine as an add-on therapy for treating benzodiazepine refractory (established) status epilepticus. In animal studies, ketamine terminates benzodiazepine refractory status epilepticus by interfering with the pathophysiological mechanisms and is a neuroprotectant.
Lisa, Coles +9 more
openaire +2 more sources
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders
JAMA psychiatry, 2017Importance Several studies now provide evidence of ketamine hydrochloride’s ability to produce rapid and robust antidepressant effects in patients with mood and anxiety disorders that were previously resistant to treatment.
G. Sanacora +7 more
semanticscholar +1 more source
The use of ketamine or ketamine–midazolam for adenotonsillectomy
International Journal of Pediatric Otorhinolaryngology, 2007Ketamine's role in clinical anaesthesia is developing as a result of the evolving concepts of its mechanism of action and the advantages of its alternative routes of administration. In this study, we aimed to investigate the frequency and severity of adverse effects, specifically emergence phenomena and vomiting, when ketamine with or without midazolam
Nezihe Ferah Donmez +3 more
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