Results 161 to 170 of about 16,187 (190)
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Exploiting metabolic susceptibilities in glioblastoma via glycolytic inhibition and ketogenic therapy.

Journal of Clinical Oncology, 2019
e13558 Background: Glioblastoma (GBM) remains one of the most lethal primary brain tumors in children and adults. Despite enormous efforts to elucidate the genetic and epigenetic drivers of this disease, the prognosis for patients diagnosed with GBM remains dismal. Because tumor cell metabolism differs greatly from that of normal non-cancerous cells,
Frederic Anthony Vallejo   +9 more
openaire   +1 more source

Low carbohydrate ketogenic therapy as a metabolic treatment for binge eating and ultraprocessed food addiction

Current Opinion in Endocrinology, Diabetes & Obesity, 2020
Purpose of review The aim of this study was to highlight the recent advancements and future directions for potential use of a low carbohydrate ketogenic dietary approach to treat binge eating and ultraprocessed food addiction. Herein, we explore proposed mechanisms of why a diet low in refined carbohydrates, processed sugar and
Shebani, Sethi   +2 more
openaire   +2 more sources

Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma?

Neurochemical Research, 2019
No major advances have been made in improving overall survival for glioblastoma (GBM) in almost 100 years. The current standard of care (SOC) for GBM involves immediate surgical resection followed by radiotherapy with concomitant temozolomide chemotherapy.
Thomas N, Seyfried   +6 more
openaire   +2 more sources

Ketogenic Diet and Metabolic Therapies

2016
Abstract Ketogenic diets have been used to treat epilepsy for nearly a century. Alongside enduring clinical success with a ketogenic diet, metabolism’s critical role in health and in diseases in the central nervous system and throughout the body is increasingly appreciated.
openaire   +1 more source

Impaired expression of ketone metabolizing enzymes in malignant gliomas: Implication for ketogenic diet therapy.

Journal of Clinical Oncology, 2012
2056 Background: Malignant glial cells may have altered expression of mitochondrial enzymes that are key for deriving energy from ketones. The novel strategy of treating malignant gliomas with a ketogenic diet has been tested in animal models with promising results.
Howard T. Chang   +2 more
openaire   +1 more source

A Pilot Study of the Spanish Ketogenic Mediterranean Diet: An Effective Therapy for the Metabolic Syndrome

Journal of Medicinal Food, 2011
The "Spanish Ketogenic Mediterranean Diet" (SKMD) has been shown to promote potential therapeutic properties for the metabolic syndrome. The purpose of this study was to evaluate the potential therapeutic properties under free-living conditions of the SKMD in patients with metabolic syndrome (following the International Diabetes Federation consensus ...
Joaquín, Pérez-Guisado   +1 more
openaire   +2 more sources

The Effect of Ketogenic Metabolic Therapy on Recurrent High-Grade Gliomas: Case Series

Journal of Neuro and Oncology Research
High-grade gliomas represent the most prevalent primary malignant brain tumors in the adult population. Despite extensive efforts dedicated to advance in therapeutic modalities, treatment options remain very limited in this field, leading to a worse prognosis for affected patients.
openaire   +1 more source

Magnetic resonance linear accelerator technology and adaptive radiation therapy: An overview for clinicians

Ca-A Cancer Journal for Clinicians, 2022
William A Hal, X Allen Li, Daniel A Low
exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen   +2 more
exaly  

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