Results 61 to 70 of about 1,349 (178)

Synthesis and Antibacterial Activity of Ketolides (6-O-Methyl-3-oxoerythromycin Derivatives):  A New Class of Antibacterials Highly Potent Against Macrolide-Resistant and -Susceptible Respiratory Pathogens

open access: yes, 2016
In the search for new antibiotics active against macrolide-resistant pneumococci and Haemophilus influenzae, we synthesized a new class of 3-oxo-6-O-methylerythromycin derivatives, so-called “ketolides”. A keto function was introduced in position 3 after
Arlette Dussarat (3022353)   +14 more
core   +1 more source

Combinatorial biosynthesis of 5-O-desosaminyl erythronolide A as a potent precursor of ketolide antibiotics

open access: yes, 2021
Ketolides, characterized by possessing a 3-keto group in place of the l-cladinose moiety of erythromycin A, are the recent generation of antimicrobials derived semi-synthetically from the 14-membered ring macrolide erythromycin A.
윤여준
core   +1 more source

Erythromycin-induced insensitivity of coagulase-negative staphylococci to telithromycin

open access: yesCurrent Issues in Pharmacy and Medical Sciences
Telithromycin represents a new group of antibiotics, called ketolides, belonging to  the same family as MLSB (macrolide, lincosamide, streptogramin B) antibiotics.
Marek Juda   +5 more
doaj  

Opioid analgesics-related pharmacokinetic drug interactions: from the perspectives of evidence based on randomized controlled trials and clinical risk management

open access: yesJournal of Pain Research, 2017
Xiu-qin Feng,1 Ling-ling Zhu,2 Quan Zhou3 1Nursing Administration Office, Division of Nursing, 2VIP Care Ward, Division of Nursing, 3Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang ...
Feng XQ, Zhu LL, Zhou Q
doaj  

QUINUPRISTIN/DALFOPRISTIN (Q/D) FOR TREATMENT OF SEVERE MULTIDRUG RESISTANT STAPHYLOCOCCUS INFECTION.

open access: yes, 1998
The fourth International Conference on the Macrolides, Azalides, Streptogramins & Ketolides.
L. MINOLI   +5 more
core  

Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides.

open access: yes, 2016
Ketolides are promising new antimicrobials effective against a broad range of Gram-positive pathogens, in part because of the low propensity of these drugs to trigger the expression of resistance genes.
DH Sherman (7940990)   +7 more
core  

In Vitro Activity of CEM-101, a New Fluoroketolide Antibiotic, against Chlamydia trachomatis and Chlamydia (Chlamydophila) pneumoniae

open access: yes, 2009
isolates each of Chlamydia trachomatis and Chlamydia (Chlamydophila) pneumoniae were tested. The MIC at which 90 % of the isolates of both C. trachomatis and C.
Charles Parker   +3 more
core  

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