Results 161 to 170 of about 1,296 (184)
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Macrolide and Ketolide Resistance with Streptococcus pneumoniae

Medical Clinics of North America, 2006
Antimicrobial agents in the macrolide family have long been considered drugs of potential utility in the management of infections caused by Streptococcus pneumoniae. However, with the emergence of macrolide resistance, the clinical value of macrolides in pneumococcal infections is threatened.
openaire   +2 more sources

[Telithromycin, first ketolide].

Revue medicale de Bruxelles, 2003
Telithromycine is the first ketolide on the market. Its characteristics are the two sites fixation on the bacterial ribosomia and and as a consequence a good activity on the majority of penicillin and macrolides resistant bacteria, included S. pneumonia and S. pyogenes.
Y, Van Laethem, J, Sternon
openaire   +1 more source

[Macrolides, ketolides and streptogramins].

Enfermedades infecciosas y microbiologia clinica, 2003
Macrolides, ketolides and streptogramins are three families of antibiotics with different chemical structures, sharing the same mechanism of action. All three bind to distinct bases of the peptidyl transferase center of ARNr 23S. Their antibacterial spectrum practically overlaps, but dissimilarities in affinity and/or number of binding sites determine ...
José, Mensa   +2 more
openaire   +1 more source

Macrolides and ketolides: azithromycin, clarithromycin, telithromycin

Infectious Disease Clinics of North America, 2004
The advanced macrolides, azithromycin and clarithromycin, and the ketolide telithromycin are structural analogues of erythromycin. They have several distinct advantages when compared with erythromycin including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once daily administration, and improved tolerability. This
openaire   +2 more sources

La telithromycine, premier ketolide

2003
info:eu-repo/semantics ...
Vanlaethem, Yves, Sternon, Jacques
openaire   +1 more source

Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides

Bioorganic and Medicinal Chemistry Letters, 2004
Xenia Beebe, Mai H Bui, Zhenkun Ma
exaly   +2 more sources

Selection of ketolide resistance in Staphylococcus aureus

International Journal of Antimicrobial Agents, 2003
S, Besier   +5 more
openaire   +2 more sources

New research in macrolides and ketolides since 1997

Expert Opinion on Investigational Drugs, 1999
André Bryskier, A Bryskier
exaly  

Synthesis of novel 5-O-(6′-O-modified)-desosamine 14-membered ketolides

Chinese Chemical Letters, 2019
Zhehui Zhao, Pingsheng Lei
exaly  

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