Results 161 to 170 of about 1,296 (184)
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Macrolide and Ketolide Resistance with Streptococcus pneumoniae
Medical Clinics of North America, 2006Antimicrobial agents in the macrolide family have long been considered drugs of potential utility in the management of infections caused by Streptococcus pneumoniae. However, with the emergence of macrolide resistance, the clinical value of macrolides in pneumococcal infections is threatened.
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[Telithromycin, first ketolide].
Revue medicale de Bruxelles, 2003Telithromycine is the first ketolide on the market. Its characteristics are the two sites fixation on the bacterial ribosomia and and as a consequence a good activity on the majority of penicillin and macrolides resistant bacteria, included S. pneumonia and S. pyogenes.
Y, Van Laethem, J, Sternon
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[Macrolides, ketolides and streptogramins].
Enfermedades infecciosas y microbiologia clinica, 2003Macrolides, ketolides and streptogramins are three families of antibiotics with different chemical structures, sharing the same mechanism of action. All three bind to distinct bases of the peptidyl transferase center of ARNr 23S. Their antibacterial spectrum practically overlaps, but dissimilarities in affinity and/or number of binding sites determine ...
José, Mensa +2 more
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Macrolides and ketolides: azithromycin, clarithromycin, telithromycin
Infectious Disease Clinics of North America, 2004The advanced macrolides, azithromycin and clarithromycin, and the ketolide telithromycin are structural analogues of erythromycin. They have several distinct advantages when compared with erythromycin including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once daily administration, and improved tolerability. This
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La telithromycine, premier ketolide
2003info:eu-repo/semantics ...
Vanlaethem, Yves, Sternon, Jacques
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Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides
Bioorganic and Medicinal Chemistry Letters, 2004Xenia Beebe, Mai H Bui, Zhenkun Ma
exaly +2 more sources
A journey across the sequential development of macrolides and ketolides related to erythromycin
Tetrahedron, 2006Sarbani Pal
exaly
Selection of ketolide resistance in Staphylococcus aureus
International Journal of Antimicrobial Agents, 2003S, Besier +5 more
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New research in macrolides and ketolides since 1997
Expert Opinion on Investigational Drugs, 1999André Bryskier, A Bryskier
exaly
Synthesis of novel 5-O-(6′-O-modified)-desosamine 14-membered ketolides
Chinese Chemical Letters, 2019Zhehui Zhao, Pingsheng Lei
exaly

