Results 11 to 20 of about 1,296 (184)
Dead Bugs Don’t Mutate: Susceptibility Issues in the Emergence of Bacterial Resistance
The global emergence of antibacterial resistance among common and atypical respiratory pathogens in the last decade necessitates the strategic application of antibacterial agents.
Charles W. Stratton
doaj +2 more sources
Ketolides--the modern relatives of macrolides : the pharmacokinetic perspective
As with other widely used antibacterials, the abundant use of macrolides for management of ambulant infections has promoted emergence of resistance against them.
Heinisch, B, Zeitlinger, M, Wagner, C C
core +4 more sources
Macrolides and ketolides are characterized by a very wide tissular distribution, which is related to their capacity to accumulate in the acidic compartments of the cells. This property is considered an advantage, because it concentrates the drug at the site of infection.
Françoise Van Bambeke
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Macrolides, Azalides, and Ketolides
The macrolides and azalides are a generally well-tolerated class of antimicrobials used to treat several mild-to-moderate infections associated with Gram-positive microorganism. Over 50 years of clinical experience with the macrolides has also led to the observation of non-antimicrobial properties that are now being exploited in clinical practice.
Manjunath P. Pai
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The macrolides and ketolides represent a class of antibacterial agents with activities against most Gram-positive and selected Gram-negative as well as atypical pathogens including penicillin-resistant microorganisms. Erythromycin, clarithromycin, and azithromycin, the most extensively used macrolides in North America, and the only approved ketolide ...
Michael T. Flavin +2 more
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From gut to mud: dissemination of antimicrobial resistance between animal and agricultural niches
Summary With increasing reports on antimicrobial resistance (AMR) in humans, animals and the environment, we are at risk of returning to a pre‐antibiotic era. Therefore, AMR is recognized as one of the major global health threats of this century. Antibiotics are used extensively in farming systems to treat and prevent infections in food animals or to ...
Niti B. Jadeja, Anja Worrich
wiley +1 more source

