Results 31 to 40 of about 1,312,198 (258)
Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules
Journal of Chemical Technology &Biotechnology, EarlyView.Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal +2 more
wiley +1 more source
Mobile Health Apps to Facilitate Self-Care: A Qualitative Study of User Experiences.
PLoS ONE, 2016 ObjectiveConsumers are living longer, creating more pressure on the health system and increasing their requirement for self-care of chronic conditions.
Kevin Anderson +2 more
doaj +1 more source
Last‐minute coordination: Adapting to demand to support last‐mile operations
Journal of Operations Management, Volume 71, Issue 2, Page 176-194, March 2025.Abstract In the highly competitive e‐commerce industry, customer‐facing warehouses are crucial as the “order penetration points” for e‐commerce last‐mile operations. This research examines how warehouses use last‐minute coordination, an unstructured mechanism, to ensure sufficient inventory at the order penetration points. Previous research has focused
Kedong Chen +3 more
wiley +1 more source
Quarterly Journal of the Royal Meteorological Society, EarlyView.Neighborhood methods are commonly used in verification to avoid the double‐penalty issue. This study evaluates such methods for the assimilation of infrared and visible satellite observations and extends them to multiscale assimilation. Moreover, a novel technique is tested aimed at mitigating complex biases and structural errors in real‐world model ...
Lukas Kugler +4 more
wiley +1 more source
TECHNIQUES FOR GUIDING THE ALLOCATION OF RESOURCES AMONG RURAL RESEARCH PROJECTS: STATE OF THE ART
Prometheus, 1983 Diverse methods are available for evaluating benefits and costs of rural research projects. They have been developed in response to a felt need for information in a highly uncertain environment.
Jock R. Anderson, Kevin A. Parton
doaj +1 more source
Facilitating System Change With GOSR: Integrating AI and Human Collaboration
Systems Research and Behavioral Science, EarlyView.ABSTRACT Problem solving in complex domains requires approaches that encourage systems thinking, collaboration, and recognize multiple simultaneous solutions. Building from principles of General Systems Theory and existing problem structuring methods, we present a new method for supporting system partners working to address complex problems called GOSR.
Annika Voltan, Kevin Kells
wiley +1 more source
Local and distributed cortical markers of effort expenditure during sustained goal pursuit
NeuroImage, 2021 The adaptive adjustment of behavior in pursuit of desired goals is critical for survival. To accomplish this complex feat, individuals must weigh the potential benefits of a given action against time, energy, and resource costs.
Lauren M. Patrick +2 more
doaj +1 more source
Review on powder-based electron beam additive manufacturing technology
Manufacturing Review, 2014 This paper presents a thorough literature review of the powder-based electron beam additive manufacturing (EBAM) technology. EBAM, a relatively new additive manufacturing (AM) process, can produce full-density metallic parts directly from the electronic ...
Gong Xibing, Anderson Ted, Chou Kevin
doaj +1 more source
Roger W. Anderson, PhD, Oral History Interview, May 18, 2004 [PDF]
, 2004 Major Topics Covered: Career at MD Anderson The history of the Pharmacy Division Integrating pharmacists within departments at MD Anderson including Nursing and Developmental Therapeutics Pharmacist\u27s role in improving chemotherapy drugs and safety ...
Anderson, Roger W., PhD +1 more
core
Journal of Animal Ecology, EarlyView.Using Structure‐from‐Motion photogrammetry in a longitudinal study, we show that although coral reef habitat complexity had declined significantly by the end of the most prolonged tropical marine heatwave on record, no further losses were detected and 3 years later the reef had begun to recover this critical ecosystem function.
Kevin A. Bruce +4 more
wiley +1 more source