A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Is caching the key to exclusion in corvids? The case of carrion crows (Corvus corone corone) [PDF]
, 2011 Sandra Mikolasch +2 more
openalex +1 more source
The moral layer of contemporary economics: A virtue-ethics perspective [PDF]
This paper questions whether the contemporary science of economics and its recommendations are built on sound moral foundations as assessed from a virtue-based definition of ethical behaviour.
vranceanu, radu
core +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Management Accounting Change in the Public Sector: A French Case Study and a New Institutionalist Perspective [PDF]
In this case study, we analyze in a French public company the adoption mode of a new management control system pertaining to New Public Management principles.
Bourguignon, Annick +2 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Combining Key-Points-Based Transfer Learning and Hybrid Prediction Strategies for Dynamic Multi-Objective Optimization [PDF]
, 2022 Yong Wang, Kuichao Li, Gai‐Ge Wang
openalex +1 more source
Coupling Performance Measurement and Collective Activity: The Semiotic Function of Management Systems. A Case Study [PDF]
Theories about management instruments often enter dualistic debates between structure and agency: do instruments determine the forms of collective activity (CA), or do actors shape instruments to their requirements, or are instruments and concrete ...
Gehrke, Ingmar, Lorino, Philippe
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Key determinants of the quality of business environment of SMEs in the Czech Republic
, 2017 Zuzana Virglerová +4 more
openalex +1 more source