Results 91 to 100 of about 6,408,925 (282)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia   +10 more
wiley   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

Other title: Efficiency Audit of the Frontenac School District

open access: yes, 2016
application/pdf; "July 2016."; "A Report to the Legislative Post Audit Committee"--Cover."K.S.A. 46-1133 requires the Legislative Division of Post Audit to conduct a series of efficiency audits of Kansas school districts from fiscal year 2014 to ...
Zimmerman, Heidi.
core   +1 more source

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

open access: yesAdvanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Other title: Efficiency Audit of the Maize School District

open access: yes, 2016
application/pdf; "July 2016."; "A Report to the Legislative Post Audit Committee"--Cover."K.S.A. 46-1133 requires the Legislative Division of Post Audit to conduct a series of efficiency audits of Kansas school districts from fiscal year 2014 to ...
Zimmerman, Heidi.
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Other title: Efficiency Audit of the Attica School District

open access: yes, 2016
application/pdf; "July 2016."; "A Report to the Legislative Post Audit Committee"--Cover."K.S.A. 46-1133 requires the Legislative Division of Post Audit to conduct a series of efficiency audits of Kansas school districts from ...
Zimmerman, Heidi.
core   +1 more source

Three essays on key audit matters dissimilarity

open access: yes
Ma thèse se compose de trois essais rapportés dans trois chapitres différents, chacun lié à une question de recherche différente sur la section des Key Audit Matters (KAMs, en français, points clés d’audit) dans les rapports d’audit.
openaire   +2 more sources

Formation, Transformation, and Synergistic Interplay of Crystalline Orientation in Conjugated Polymers via Solution‐State Aggregation Control

open access: yesAdvanced Science, EarlyView.
Molecular engineering (i.e., tuning donors) and three film processing strategies (i.e., drop‐casting from different solvents, thermal and solvent vapor annealing, and blending) were synergistically utilized to tailor the solution‐state aggregation and thus the formation, transformation, and interplay of solid‐state crystalline orientation (face‐on and ...
Hao Zheng   +9 more
wiley   +1 more source

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