Results 91 to 100 of about 7,346,603 (351)

European reference framework of key competences for lifelong learning: an updated 2018 version

open access: yesUkrainian Educational Journal, 2019
The author noted the importance for the European education of the European reference framework of key competencies for lifelong learning (2006) and its impact on the development of education in Ukraine. The synchronization of the vision of the competency
O. Lokshyna
semanticscholar   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Identificación de competencias en edición para los profesionales de la información [PDF]

open access: yes, 2006
The identification of competences constitutes one of the key dimensions inside the management of competences. Its objective is to determine the competences an individual requires to excellently perform a specific activity. The present tendencies in the
Díaz Alvarez, Yuniar Yaneris   +1 more
core  

The Framework Catalogue of Digital Competences [PDF]

open access: yes, 2015
The Framework Catalogue of Digital Competences Justyna Jasiewicz, Mirosław Filiciak, Anna Mierzecka, Kamil Śliwowski, Andrzej Klimczuk, Małgorzata Kisilowska, Alek Tarkowski & Jacek Zadrożny Centrum Cyfrowe Projekt: Polska ...
Filiciak, Mirosław   +7 more
core   +6 more sources

Key competences for Transport 4.0 – Educators’ and Practitioners’ opinions

open access: yesOpen Engineering, 2022
This study deals with the subject of the Fourth Industrial Revolution; that is, Industry 4.0 or Revolution 4.0 discusses its impact on contemporary road transport and the development of Transport 4.0.
Gąsiorek Kamila
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Developing the methodological instructions of art education supporting key competences and subject-specific competence

open access: yesEesti Haridusteaduste Ajakiri
Eesti õpetajad on hästi ette valmistatud aine õpetamiseks, kuid ebakindlamalt tuntakse end kunsti osaoskuste ja üldpädevuste seostamisel. Eesti uuendatud riiklik õppekava näeb kunsti ainekavas ette ainepädevuse ja üldpädevuste ühendamist.
Helen Arov   +3 more
doaj   +1 more source

Structure of Personality Properties and Its Contribution to Long-Term Employability [PDF]

open access: yesSocietas et Iurisprudentia, 2014
The paper deals with the importance of the properties that make up the structure of personality to an individual’s long-term employability. The topic is a response to an enduring problem on the labour market in Slovakia, namely unemployment of university
Marta Matulčíková   +1 more
doaj  

Home - About - Disclaimer - Privacy