Results 91 to 100 of about 28,836 (311)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Talent management

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2006
The contribution describes the methodology of work with human assets, and namely talent management representing a system of work with employees having over-average potential and representing the source of competitive advantage for the company.
Tomáš Kroupa
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Towards a clearer delimitation of internal European Community competences.

open access: yes, 2006
This thesis is a study of the distribution of competences between the main actors in European integration: namely the European Community and the Member States.
Konstadinides, T, Konstadinides, T.
core  

Schooling and Lifelong Learning. The Role of Transversal Key Competences

open access: yes, 2014
The purpose of this paper is to consider the process of developing transversal key competences to achieve long term goals such as citizenship, social cohesion and lifelong learning.I examine the role that key competences play in the recent reformed ...
Zadra, Cinzia
core   +1 more source

EUROPEAN UNION EXTERNAL COMPETENCES PRACTICE KEY DETERMINANTS

open access: yesЭлектронное приложение к Российскому юридическому журналу, 2023
Laptsenak Violetta
doaj   +1 more source

The identification of key competencies of university graduates

open access: yesStudia Humanitatis, 2015
The article focuses on problems of key competences identification of university graduates in the view of existing approaches to definitions of “competence” and “key competence”.
Eremina Anastasia Vitalievna   +2 more
doaj  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Comparison of key competences of DB clients and contractors in the construction market of the People’s Republic of China

open access: yes, 2012
Clients and Design-build (DB) contractors are two key stakeholders in DB projects, and contribute significantly to the successful project performance.
Zuo, Jian, Xia, Bo, Chan, Albert
core  

The key project managers’ competences for different types of projects

open access: yes, 2014
This paper describes a quantitative research approach for identifying key project managers’ competences for different types of projects. By identifying the perceived most valuable project manager competences, as having the most potential for increased
Fernandes, A. Gabriela   +7 more
core   +1 more source

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