Results 71 to 80 of about 2,783,643 (311)
Improving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix
Drug Delivery, 2017 In the present study, we select the Sylysia 350 (Sylysia) as mesoporous material, distearoylphosphatidylethanolamine-poly(ethylene glycol)2000 (DSPE-PEG) as absorption enhancer and hydroxy propyl methyl cellulose (HPMC) as crystallization inhibitor to ...
Yang Guo +9 more
doaj +1 more source
Collaboration on a grand scale: facilitating the transition of first year students into higher education [PDF]
, 2008 This article describes the development and delivery of a new research and study skills module delivered to all students in an undergraduate degree programme in Dublin City University.
Dunne, Siobhán
core
Simulation modeling of tool delivery system in a machining line [PDF]
, 2011 This paper describes an industrial project aiming to enhance the existing simulation modeling suites used at a car engine factory in the UK. The company continues to enhance its simulation modeling capabilities towards so called the `total plant modeling'
Ladbrook, J., Tjahjono, Benny
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego +10 more
wiley +1 more source
Nature Communications, 2022 Detailed quantification of nanoparticle distribution in tumor tissues can provide the prediction of drug delivery efficacy and therapeutic outcome. Here the authors develop a pH/light dual responsive monochromatic ratiometric-imaging nanoparticle which ...
Yue Yan +13 more
doaj +1 more source
Land Use Strategy (LUS) Delivery Evaluation Project : Volume 1: Main Report [PDF]
, 2014 Scotland’s first Land Use Strategy (LUS) – Getting the best from our land – was published in March 2011. The LUS is a requirement of the Climate Change (Scotland) Act 2009, highlighting the important contribution that Scottish Ministers expect land use ...
Baker, Jonathan +4 more
core
Digital microfluidics with pressure-based actuation [PDF]
, 2013 One of the key issues in biosensors is the time it takes for biomolecules in a solution to reach and bind to the sensor surface (particularly in low-concentration analytes).
Bienstman, Peter, Hallynck, Elewout
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason +14 more
wiley +1 more source
Drugs in R&DTherapeutic efficacy for malignancies and neurological disorders is fundamentally restricted by biological barriers, particularly the complex tumor microenvironment (TME) and selective blood–brain barrier (BBB).
Yicong Lei +3 more
doaj +1 more source
Outer membrane vesicles: Versatile nanocarriers for therapeutic delivery and immune modulation
Acta Pharmaceutica Sinica BOuter membrane vesicles (OMVs) are nanoscale lipid-bilayer vesicles naturally released by Gram-negative bacteria. By packaging membrane proteins, lipopolysaccharide-derived pathogen-associated molecular patterns, nucleic acids, and metabolites, OMVs ...
Jinlong Yang +6 more
doaj +1 more source