Results 71 to 80 of about 7,763,303 (316)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Characterisation of 2-HP-β-cyclodextrin-PLGA nanoparticle complexes for potential use as ocular drug delivery vehicles

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Aim 2-HP-β-cyclodextrin-PLGA nanoparticle complexes were prepared to enhance the aqueous humour delivery of Triamcinolone acetonide.Materials & methods Drug-loaded 2-HP-β-CD/PLGA nanoparticle complexes prepared by adapting a quasi-emulsion solvent ...
Fan Li, Yuqin Wen, Yan Zhang, Kangyu Zheng, Junfeng Ban, Qingchun Xie, Yifeng Wen, Qing Liu, Fohua Chen, Zhenjie Mo, Lizhong Liu, Yanzhong Chen, Zhufen Lu   +12 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Leveraging engineered mitochondria through intercellular communication network for accelerated transport and delivery

Nature Communications
Inspired by the non-transmembrane transfer of mitochondria in cell-to-cell communications, herein, we report an original exploration to accelerate mitochondrial intercellular transport, and its application to exogenous cargo delivery.
Yiwei Peng, Datong Gao, Yiliang Yang, Yitian Du, Zhenzhen Yang, Jiajia Li, Meng Lin, Yanxia Zhou, Xinru Li, Xianrong Qi   +9 more
doaj   +1 more source

Auto Delivery Moving Company (1911)

, 1911
Best furniture and piano moving equipment in the city. All work done by auto, insuring quicker and safer delivery. Our auto service insures prompt delivery of trunks and baggage.Automobiles, carriages and wagons Commercial and professional services ...
Auto Delivery Company
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Microglial double stranded DNA accumulation induced by DNase II deficiency drives neuroinflammation and neurodegeneration

Journal of Neuroinflammation
Background Deoxyribonuclease 2 (DNase II) is pivotal in the clearance of cytoplasmic double stranded DNA (dsDNA). Its deficiency incurs DNA accumulation in cytoplasm, which is a hallmark of multiple neurodegenerative diseases.
Ling-jie Li, Shi-yu Liang, Xiao-ying Sun, Jie Zhu, Xiao-yun Niu, Xiao-yu Du, Ya-ru Huang, Rui-tian Liu   +7 more
doaj   +1 more source

Volatile Oils from Natural Plants: Promising Penetration Enhancers for Biological Barriers

Pharmaceutical Fronts
Drug delivery often faces challenges from biological barriers, including the skin and mucosa. Penetration enhancers (PEs) are commonly employed to improve the delivery of poorly permeable drugs.
Xinyu Ma, Yu Jin, Miao Wang, Shiyu Zong, Yunlong Cheng, Hong Zhang, Wei Wu, Yi Lu, Ye Li, Chunliu Wang   +9 more
doaj   +1 more source