FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
RIS-Enabled Secret Key Generation for Secured Vehicular Communication in the Presence of Denial-of-Service Attacks. [PDF]
Sensors (Basel), 2023 Shawky MA +7 more
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
State-of-the-art session key generation on priority-based adaptive neural machine (PANM) in telemedicine. [PDF]
Neural Comput Appl, 2023 Dey J.
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A High-Entropy True Random Number Generator with Keccak Conditioning for FPGA
SensorsAny cryptographic system strongly relies on randomness to ensure robust encryption and masking methods. True Random Number Generators play a fundamental role in this context. The National Institute of Standards and Technology (NIST) and the Bundesamt für
Valeria Piscopo +4 more
doaj +1 more source
An anti-collusion attack defense method for physical layer key generation scheme based on transmission delay. [PDF]
PeerJ Comput Sci, 2023 Wang X, Huang J, Qi C, Peng Y, Zhang S.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Identity-Based Proxy Re-Encryption Scheme Using Fog Computing and Anonymous Key Generation. [PDF]
Sensors (Basel), 2023 Lin HY, Tsai TT, Ting PY, Fan YR.
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source