Results 61 to 70 of about 1,214,320 (245)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Improvement of the Minimal-Guess-Basis MILP Model and Its Application to ESF

IET Information Security
The guess-and-determine technique find wide applications in the recovery of unknown variables within given system of relations. The fundamental concept behind this technique involves guessing certain unknown variables and deducing the remaining ones ...
Lingchen Li, Zhi Qiao, Yiming Dai, Yongzhuang Wei, Tao Ye   +4 more
doaj   +1 more source

Developing a model for rehabilitation in the home as hospital substitution for patients requiring reconditioning: a Delphi survey in Australia

BMC Health Services Research, 2023
Background Reconditioning for patients who have experienced functional decline following medical illness, surgery or treatment for cancer accounts for approximately 26% of all reported inpatient rehabilitation episodes in Australia. Rehabilitation in the
Roslyn G Poulos, Andrew M Cole, Kerry N Warner, Steven G Faux, Tuan-Anh Nguyen, Friedbert Kohler, Fey-Ching Un, Tara Alexander, Jacquelin T Capell, Dan R Hilvert, Claire MC O’Connor, Christopher J Poulos   +11 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Delphi consensus recommendations for a treatment algorithm in pulmonary sarcoidosis

European Respiratory Review, 2020
Pulmonary sarcoidosis presents substantial management challenges, with limited evidence on effective therapies and phenotypes. In the absence of definitive evidence, expert consensus can supply clinically useful guidance in medicine.
Franck F. Rahaghi, Robert P. Baughman, Lesley Ann Saketkoo, Nadera J. Sweiss, Joseph B. Barney, Surinder S. Birring, Ulrich Costabel, Elliott D. Crouser, Marjolein Drent, Alicia K. Gerke, Jan C. Grutters, Nabeel Y. Hamzeh, Isham Huizar, W. Ennis James, Sanjay Kalra, Susanna Kullberg, Huiping Li, Elyse E. Lower, Lisa A. Maier, Mehdi Mirsaeidi, Joachim Müller-Quernheim, Eva M. Carmona Porquera, Lobelia Samavati, Dominique Valeyre, Mary Beth Scholand   +24 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Post-Quantum Encryption Algorithms

Acta Electrotechnica et Informatica
The most used asymmetric encryption algorithm nowadays is RSA. It may become insecure regarding advances in the field of quantum computers. It is the reason why the National Institute of Standards and Technologies introduces the challenges of choosing a ...
Pekarčík Peter, Chovancová Eva
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A New Cipher Based on Feistel Structure and Chaotic Maps

مجلة بغداد للعلوم, 2019
Chaotic systems have been proved to be useful and effective for cryptography. Through this work, a new Feistel cipher depend upon chaos systems and Feistel network structure with dynamic secret key size according to the message size have been proposed ...
Al-Bahrani et al.
doaj   +1 more source